The circular dichroism (cd) spectra of nineteen aporphines of widely differing substitution patterns have been examined between 200 and 400 nm. Three major cd band systems exist, in the 220, 270-280, and 300 nm region. Two intense oppositely-signed Cotton effects (CE's) between 200 and 250 nm are substitutionindependent and configuration-dependent, as is the third CE at 270-283 nm. In the region 293-327 nm, there are two further CE's which are substitution-dependent. In the case of symmetrically (1,2,10,11) substituted aporphines, the bands in the 300 nm region are split into two oppositely-signed CE's with a pattern similar to that observed for the 220 nm region. 'Publication No. 30 in the series Optical Rotatory Dispersion and Absolute Configuration, 80 Cd spectra were measured in 95% ethanol on a Roussel-Jouan Mark II dichrograph or a Jasco ORD-CD5 spectropolarimeter at 20°.

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Die Totalsynthese von Splendidin (VII) erfolgt ausgehend vom Tetrahydroisochinolin (I), das in das Isochinolin (III) übergeführt wird.

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