Cavitation in pulmonary metastases is more common than might be supposed from the small number of cases (75) (Farrell, 1935;Efskind and Wexels, 1952). Minor (1950), in a series of 314 cases with lung secondaries, found only four nodular carcinomatous metastases with evidence of cavitation. LeMay and Piro (1965) observed that the primary in cases of cavitary pulmonary metastases may be in any part of the body.
METHODS AND MATERIALSTwenty-five cases of cavitating pulmonary metastases were observed in a combined radiological and histological survey covering the years 1964 to 1969 at the London Chest Hospital. The lungs received from the operating theatre or the postmortem room were fixed and sliced so that the relation of the necrotic areas to the bronchi could be explored. Blocks were chosen for microscopical examination. Besides haematoxylin and eosin stain, Verhoeff-van Gieson was used to evaluate the vascular factor.
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