Astrup, P., Rorth, M. & Thorshauge, C. Dependency on Acid-base Status of Oxyhemoglobin Dissociation and 2,3-Diphosphoglycerate Level in Human Erythrocytes. 11. In Vivo Studies. Scand. 1. clin Lab. Invest. 26, [47][48][49][50][51][52] 1970.The intraerythrocytic level of 2,3-diphosphoglycerate and the oxygen affinity of hemoglobin in the red cell are shown to be strongly dependent on the intraerythrocytic pH. This effect should be taken into account when evaluating the increase in 2,3-diphosphoglycerate found at hypoxemic and anemic hypoxia. It was also demonstrated that high concentrations of inorganic phosphate in serum influence the intraerythrocytic 2,3-diphosphoglycerate concentration.tions of acid-base status, intraerythrocytic pH, Tao value, concentration of 2,3-DPG and of other blood constituents. Frequently the analyses were repeated on following days. All the Scand J Clin Lab Invest Downloaded from informahealthcare.com by Cornell University on 12/26/14For personal use only.

No abstract

No abstract