No abstract

Two Ojibwa Indian populations in Ontario, selected to represent the Northern (Pikangikum Band) and Southeastern (Wikwemikong Band) branches of this “tribe” are compared for their serum protein and red cell enzyme systems. Albumin, haptoglobin, immunoglobins Gm and Inv, serum α‐globulin and transferrin polymorphisms are reported. The genetic markers AlNaskapi and GcChippewa are found in both groups, TfD Chi in Pikangikum only. Contrary to expectations, the Mongoloid marker Gm1,3,5,11 was found in neither population. Ceruloplasmin is invariant in both, all individuals being B homozygotes. For the red cell enzymes, only the common phenotypes of glucose 6‐phosphate dehydrogenase and peptidases A and B are present in the Northern and Southeastern Ojibwa. Isocitrate dehydrogenase, lactate dehydrogenase, nucleoside phosphorylase, phosphofructokinase, phosphoglucomutase II, phosphoglyeerate kinase and peptidase C were typed in Pikangikum only: no variants were found. Methemoglobin reductase, tested in Wikwemikong alone, is invariant. Loci polymorphic in at least one Ojibwa group include acid phosphatase, adenosine deaminase, adenylate kinase, glutathione reductase, phosphogluconate dehydrogenase, phosphoglucomutase I, and soluble glutamic oxalocetic transaminase. Comparisons are made with other Algonkian‐speakers when possible, with other North American, South American and Asiatic Mongoloid populations when sufficient Algonkian data do not exist. The causes of genetic heterogeneity between the two Ojibwa groups are discussed.

The distribution of Glm(f, z, a, and x), G3m(b0, b1, b3, c3, c5, g, s, and t) and Km(1) (formerly Inv[1]) allotypic markers have been examined in 184 Hungarians. The results indicate that the frequency of the immunoglobulin haplotypes Gm^za;g, Gm^zax;g, Gm^f;b and Km¹ is similar to the frequencies observed in surrounding populations. In addition, Hungarians were found to be polymorphic for the Oriental haplotype Gm^za;bst, and had low frequencies of other uncommon haplotypes. Our data indicate that about 5% of the Hungarian genome is of Oriental origin.

Abstract. A new antigenic determinant on the majority of human IgG3 is described. The new antigen is found in the sera of all Gm(g)‐positive individuals and the majority of Gm(b)‐positive individuals. Only those individuals homozygous for Gm(c5) are negative for the new antigen. Family studies verify the inheritance and indicate that the new antigen behaves as an alternate substitution to Gm(c5) in man.

The distributions of Gm(a, x, f, b, c, g, and t) and Inv(l) allotypic markers have been examined in 512 Chinese classified as to province of origin. The results indi cate a south to north cline, extending from southernmost to northern China in which Gm^ag changes from 0.12 to 0.55, Gm^axg from 0.04 to 0.15, Gm^abst from 0.04 to 0.12 and Gm^afb from 0.80 to 0.22. In contrast to the Gm system, there does not appear to be any significant regional variation in the frequency of Inv¹ among Chinese.