An efficient and enantioselective synthesis of oxa[9]helicenes has been established via vanadium(V)-catalyzed oxidative coupling/intramolecular cyclization of polycyclic phenols. A newly developed vanadium complex cooperatively functions as both a redox and Lewis acid catalyst to promote the present sequential reaction and afford oxa[9]helicenes in good yields with up to 94% ee.

A highly atom-economical enantioselective Rauhut–Currier and [3+2] annulation has been established by flow system and machine-learning-assisted exploration of suitable conditions.

Enantioselective oxidative-coupling of polycyclic phenols such as 2-anthracenol, 9-or 3phenanthrol, and 5-chrysenol was established by using vanadium(V/IV) catalysis under air or O2 as a co-oxidant. In the vanadium catalyzed reaction, the corresponding coupling products were obtained in good to excellent yields with up to 93% enantiomeric excess.

In this paper, the dehydrogenation of tetrahydroquinolines using oxovanadium(V) catalysts under mild conditions in water and oxygen atmosphere is described. This catalytic technology was successfully applied to a range of other structurally related N-heterocycles, and a reaction mechanism is proposed.

The catalytic enantioselective oxidative hetero-coupling of arenols using a chiral vanadium(v) complex has been developed. The coupling of hydroxycarbazole derivatives with various arenols provided axially chiral biarenols in high chemo-,...