Background:Light-based detection agents using autofluorescence may be helpful in the detection of early dysplasia, which would otherwise be misdiagnosed as nondysplastic by conventional oral examination (COE) with white light. Visually-enhanced lesion scope (VELscope) is one of such an aid used for the purpose. A meta-analysis was carried out on the sensitivity and specificity of VELscope that would enable in providing evidence of its usage in oral dysplasia.Materials and Methods:MeSH terms such as auto florescence in oral dysplasia, VELscope, Oral ID, Identifi, in a different medical database such as PubMed, Cochrane, EBSCO, and Google scholar was carried out by four research associates. The total articles available were 242, of which, 230 were excluded based on strict criteria of randomized control trials and proper design. Finally, only 12 studies were chosen for the present analysis. Of 1643 patients from 12 studies, 1264 patients had undergone the autofluorescence examination after the COE. Only 774 patients have shown the loss of fluorescence with VELScope examination and 487 had retained the fluorescence. Biopsy was performed on 1176 patients after the autofluorescence examination in the areas where there was the loss of fluorescence. The available data were subjected to software Review Manager for analysis.Results and Discussion:Of the 11 studies analyzed, majority of them showed that the autofluorescence device were sensitive enough > 0.70; however, the values of sensitivity and specificities varied significantly. With the VELscope the diagnostic performance of the inexpert examiner was not improved, obtaining a sensitivity of 0.40 (95% of confidence interval [CI]: 0.406–0.773) and a specificity of 0.80 (95% CI: 0.614–0.923).Conclusion:The new technique may help as an adjunct to histopathology in detecting the dysplasia initially and stop further progression to the carcinoma.

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One of the most important aspects of postsurgical care is finding an efficient way for the management of pain. Third molar extractions/surgical impaction is one of the most frequent surgical procedures in dental hospitals, and it is most often associated with postoperative complications like severe pain, oedema and reduced mouth opening. This study was aimed to evaluate the efficacy of 2 g intravenous Analgesic Effect of intravenous Ascorbic Acid Versus Acelcofenac Post-Transalveolar Extraction: A case-control study

Angiomyofibroblastoma (AMF) is a rare soft tissue tumor with unique morphological features occurring in the vulvo vaginal region of women. Few reported cases of occurrence in men. The tumor is localized in the scrotum &in the inguinal area of male patients. It is often mistaken for Bartholin's gland cyst in women. We report a case of Angiomyofibroblastoma of vulva in a 46 yrs old woman.

Original Research ArticleStudy of maternal and perinatal outcome among twin pregnancies with one twin demise Sunanda N.*, Akhila M. V. INTRODUCTIONFetal loss of a twin during the first trimester is not an uncommon event. 1 However, fetal death occurring in the second or third trimester is rare with a reported incidence ranging from 0.5% to 6.8%. 1 Management of such cases is challenging to the obstetrician especially in cases of preterm single death, where the risk of fetal prematurity complications must be weighed against the possible intrauterine complications in the surviving fetus. The risk of mortality and morbidity in the surviving twin is considerable and depends on the cause, time of the death and also on the type of placentation. There is increased risk of IUGR, preterm labor, preeclampsia, survival with cerebral impairment and perinatal mortality. 2 The causes of fetal death vary and include twin-twin transfusion, placental insufficiency, intrauterine growth retardation related to preeclampsia, velamentous insertion of the cord, cord stricture, cord around the neck, and congenital abnormalities. 2 In general, chorionicity rather than zygosity determines the risk of mortality and the morbidity with increased prevalence in monochorionic ABSTRACT Background: To study the incidence, management and to determine maternal and perinatal outcome in cases of twin pregnancy with one twin demise in the second half of the pregnancy. Methods: This retrospective study was carried out at Cheluvamba Hospital, a tertiary care hospital attached to Mysore medical college and research institute between September 2009 and 2014. 19 twin pregnancies complicated by single intrauterine fetal demise (IUFD) after 20 weeks of gestation were identified from the hospital records. Data collected included maternal age, parity, antenatal complications, cause of IUFD, gestational age at diagnosis, time interval between diagnosis of IUFD and delivery, mode of delivery, birth details, type of placentation and neonatal complications.Results: The incidence of twin with one twin demise was 2.056%. Mean gestational age at presentation was 33.86 weeks. Most common cause of death was growth discordance in 7 cases followed by placental insufficiency in 4 cases. 57.89% of cases had monochorionic placentation. Neonatal course was most commonly complicated by prematurity. Maternal course was uneventful in majority (63.15%) of cases with two maternal deaths due to intravascular coagulopathy sequelae. Conclusions: Single fetal death occurs more often in monochorionic twins. The main problem for the surviving twin is prematurity. It is very important to identify the chorionicity by ultrasound examination in early pregnancy and implement specific surveillance of monochorial pregnancies.