A man who, only in 1979 and on a few occasions, had homosexual contacts, transmitted AIDS virus HTLV-III in 1980 and 1981 to two previously healthy women who did not belong to any AIDS risk group. One of them now has an early form of AIDS, while the other died of AIDS in its full form and her child, born in 1983, has fairly far progressed early symptoms of AIDS. Serum antibodies against HTLV-III were demonstrated in all four subjects.
We report on the very rare case of haemolytic disease of a newborn caused by diaplacental Anti-Kidd (b) from the mother. The second child of a 30 years old woman (two births, two pregnancies) developed a marked jaundice (maximal serum bilirubin 304.5 mol/l). Other reasons for thisjaundice could be excluded. Immunization was believed to stem from pregnancy, because the mother had never been transfused. In this context an overview is given on the literature concerning cases with haemolytic disease of the newborn due to Anti-Kidd (b)
. From this and from our case we conclude that antibody screening of pregnant women should be performed either with test erythrocytes of two donors with at least 2 methods (indirect antiglobulin test with albumin and one stage enzyme test) or one method (indirect antiglobulin test with albumin technique) with test cells from 3 donors. In unclear cases of HDN matemal serum should be cross matched against patemal red cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.