These results suggest that selenium could be effective in neutralizing the damage of ethanol consumption during gestation and lactation in pups since it repairs selenium levels in liver as well as the activity of scavenging enzymes and peroxidation protein products. In serum, Se also recovers GPx activity and increases the levels of Se that are available to other organs.
This study sought to determine the intestinal in vivo absorption of folic acid and methyltetrahydrofolate (MTHF) by jejunum surface at different times, after 20 weeks of 30% ethanol ingestion. The absorption results were compared with the data of control rats. In general after ethanol treatment jejunal folic acid absorption was higher than in control rats. When the folic acid concentrations in the perfusion medium were 0.5 µM an increase at later times in ethanol-fed rats was found. At 1 µM the folic acid absorption values were significantly higher at the earlier time. When the concentration assayed was 2.5 µM, significant modifications were only seen at 30 min. Results of MTHF absorption by jejunum of ethanol-fed rats were similar to absorption values of control rats. No significant differences between both groups were found. The results obtained in the present work suggested a different absorptive behavior of both substrates and a different effect of ethanol on folic acid and MTHF absorption in the jejunum.
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