No abstract

We report an acute myelitis in a 53-year-old woman that occurred in 7 days after the diagnosis of Th5-6 herpes zoster. Clinical examination revealed hyperhidrosis of left side of her face, neck, arm and upper chest. She also had muscle weakness of her left leg and sensory impairment for light touch and temperature in her chest and legs. Spinal cord MRI demonstrated a longitudinal T 2-hyperintense lesion extending from Th1 to 7. In the axial imaging, the lesion dominantly located in the left side gray matter. Hyperhidrosis, weakness and sensory impairment were improved after intravenous therapy with acyclovir and methylprednisolone. VZV (varicella zoster virus) IgG index of the cerebrospinal fluid was high and serological anti aquaporin-4 antibodies were positive at the time of the admission. This case had both characteristics of VZV myelitis and neuromyelitis optica spectrum disorder. Myelitis relapsed 19 months after the first attack. We believe that sympathetic hyper reactivity due to thoracic spinal cord lesion was responsible for the hyperhidrosis in our patient.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Pyridine derivatives R 0380 Hilbert-Johnson Reaction under High Pressure: A Facile Preparation of 2-Pyridones. -The title reaction is sensitive to steric hindrance of haloalkanes. -(MATSUMOTO*, K.; IKEMI, Y.; SUDA, M.; IIDA, H.; HAMANA, H.; Heterocycles 72 (2007) 1, 187-190; Fac. Pharm. Sci., Chiba Inst. Sci., Choshi, Chiba 288, Japan; Eng.) -M. Bohle 38-143

Das Tetramethylcycloheptanon (I) bildet mit 2 Äquivalenten Brom das Dibromid (II), das bei der Behandlung mit Kalium‐tert.‐butylat in Tetrahydrofuran bei ‐20°C das Dehydrobromierungsprodukt (III) ergibt.