No abstract

Basal cell carcinoma (BCC) is the most frequent malignant neoplasm of the skin. If a neoplasm is recognized and an accurate treatment is implemented, the prognosis is very positive. However, negligence of the neoplasm could lead to infiltration of the adjacent bone, cartilaginous or vascular structures as well as the eyeball, which could result in its damage and anatomical deformations. The presented case illustrates the possible aggressive and destructive impact of facial skin basal cell carcinoma with rare involvement and destruction of the underlying bone. Long-term growth of the neoplasm resulted in an ulcerative lesion of the forehead area, disability, severe depression and social isolation, as well as numerous somatic complications. This article presents the issues and challenges of palliative care of a patient with advanced facial skin cancer.

Chronic sinusitis of the sphenoid sinus is a disease that can cause a number of complications, mainly intracranial and ophthalmic ones. The proximity of critical anatomical structures such as the internal carotid artery, cranial nerves, cavernous sinus, dura mater and cerebral lobes puts any or all of these at risk and challenge due to the disease process itself and in surgical management as well. Infiltration of bone structures or its damage in the mechanism of compression is recorded in cases of fungal rhinosinusitis (FRS), Wegener's granulomatosis or actinitis with manifestation in the area of the sinuses. The authors present five patients with chronic sinusitis with bone destruction of the sphenoid sinus. Suspicion of fungal etiology in all cases was based on computed tomography (CT) images. The authors pay particular attention to the role of functional endoscopic sinus surgery (FESS) in chronic sinusitis with bone destruction, especially of a fungal etiology.