Background : Most human activities cannot be separated from the use of computers. Long-term and uncontrolled use of computers can lead to Computer Vision Syndrome (CVS). According to the Ministry of Health of the Republic of Indonesia (KEMENKES) CVS can be handled with ergonomics use of computers resultantly reducing the impact of computer exposure. Education on ergonomics use of computer and PERMATA-KU exercise is expected to improve CVS scores.Research Purpose : Proving the effect of PERMATA-KU exercises toward CVS score improvementMethod : Research subjects are divided into treatment group and control group, each group consists of 15 people. The treatment group received education about the ergonomics use of computer and PERMATA-KU exercises while the control group received education on the ergonomics use of computers. The measurement’s instrument is the CVS questionnaire. The dependent variable of the study was the CVS score and the independent variable of the study was the type of treatment. Statistical test with Wilcoxon, paired t test, unpaired t test, Mann whitney and chi square. Meaning value p <0.05.Result : There was a significant difference in CVS scores before and after the intervention in the treatment group (p = 0.001) and the control group (p = 0.006). There was a significant difference in delta CVS scores between the treatment group and the control group (p=0,008). There was a significant difference in CVS scores after the intervention in the treatment group and the control group (p=0,017). There was no significant difference in the incidence of CVS after the intervention between the treatment group and the control group (p = 0.259).Conclusion : There is an effect of "PERMATA-KU" exercise on the improvement of CVS scores.