Disentangling distinct stellar populations along the red-giant branches (RGBs) of Globular Clusters (GCs) is possible by using the pseudo two-color diagram dubbed chromosome map (ChM). One of the most intriguing findings is that the so-called first-generation (1G) stars, characterized by the same chemical composition of their natal cloud, exhibit extended sequences in the ChM. Unresolved binaries and internal variations in helium or metallicity have been suggested to explain this phenomenon. Here, we derive high-precision Hubble Space Telescope photometry of the GCs NGC 6362 and NGC 6838 and build their ChMs. We find that both 1G RGB and main-sequence (MS) stars exhibit wider ChM sequences than those of second-generation (2G). The evidence of this feature even among unevolved 1G MS stars indicates that chemical inhomogeneities are imprinted in the original gas. We introduce a pseudo two-magnitude diagram to distinguish between helium and metallicity, and demonstrate that star-to-star metallicity variations are responsible for the extended 1G sequence. Conversely, binaries provide a minor contribution to the phenomenon. We estimate that the metallicity variations within 1G stars of 55 GCs range from less than [Fe/H]∼0.05 to ∼0.30 and mildly correlate with cluster mass. We exploit these findings to constrain the formation scenarios of multiple populations showing that they are qualitatively consistent with the occurrence of multiple generations. In contrast, the fact that 2G stars have more homogeneous iron content than the 1G challenges the scenarios based on accretion of material processed in massive 1G stars onto existing protostars.

Recent observational studies have demonstrated that the complex stellar system Terzan 5 (Ter 5) harbours multiple populations of stars. Several models have attempted to interpret the large age difference of several Gyrs between the dominant populations, but none have been universally accepted. We propose a new scenario whereby a collision between a metal-poor Ter 5 and a giant molecular cloud (GMC) serves as a catalyst for the generation of a super-solar population of stars. Using numerical simulations of this new "GC-GMC" collision scenario we demonstrate that, within a time frame of several Gyrs, our synthetic Ter 5 was capable of interacting with a metal-rich GMC in the central region of the Galaxy. As a consequence of this, our simulated globular cluster (GC) is able to capture enough gas from the colliding GMC to form a new population of metal-rich stars. Furthermore, the younger population created from the high-density regions of the captured gas is shown to have a stronger central mass concentration than the older metal-poor one, which is consistent with observations. A chemical link between Ter 5 and the bulge population of the Milky Way has long been observed and these simulations finally provide evidence for their similarities. Our model rationalises the 5 Gyrs of quiescence observed between the two dominant populations of Ter 5 and justifies the existence of the young generation. We discuss the advantages and disadvantages of the new scenario in the context of the observed physical properties of Ter 5.