and Nepal account for about a quarter of the world's population and contribute the highest proportion of the burden of cardiovascular diseases compared with any other region globally. [1][2][3] South Asian migrants living in several countries have higher death rates from coronary heart disease (CHD) at younger ages compared with the local population despite apparently lower levels of conventional risk factors. [4][5][6][7][8] Deaths related to cardiovascular disease also occur 5 to 10 years earlier in South Asian countries than they do in Western countries. 9,10 This has raised the possibility that South Asians exhibit a special susceptibility for acute myocardial infarction (AMI) that is not explained by traditional risk factors.Among individuals living in the United Kingdom,theearlieronsetofCHDamong

The preserved association of LDL-C with risk of AMI among Asians, despite the lower baseline levels, suggests the need to rethink treatment thresholds and targets in this population. The low HDL-C level among South Asians requires further study and targeted intervention.

This is the first repeat cross-sectional study on blood pressure (BP) in a Nepalese population. There is a very high prevalence as well as a sharp rise in HTN prevalence in this society largely because of changing lifestyle which is most likely because of socio-economic transition.

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