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Background Micronutrient deficiency is a global health burden, especially among developing countries. The present cross‐sectional study aimed to determine the prevalence of vitamin B12 deficiency in healthy Indian school‐going adolescents, based on area of residence, sex and body mass index (BMI). Furthermore, the relationship of serum B12 concentration with dietary vitamin B12 intake and anthropometric indices was assessed among adolescents from rural and urban India. Methods A total of 2403 school‐going adolescents (11–17 years) from National Capital Region and rural areas of Haryana, India were selected. Serum B12 concentrations were estimated using an electrochemiluminescence immunoassay. Dietary assessments were conducted on 65% of total participants (n = 1556) by two 24‐h diet recalls. Results The prevalence of vitamin B12 deficiency in the total study population was 32.4% (rural: 43.9% versus urban: 30.1%, P < 0.001; male: 34.4% versus female: 31.0%, P < 0.05; normal weight: 28.1%, versus overweight: 39.8%, versus obese: 51.2%, P < 0.001). More than half (51.2%) of obese adolescents were vitamin B12 deficient. On multiple linear regression analysis, serum B12 in rural adolescents was associated with age (β = −0.12, P < 0.05). Among urban adolescents, serum B12 was associated with BMI (β = −0.08, P < 0.05) and adjusted dietary vitamin B12 intake (β = 0.14, P < 0.001). Serum vitamin B12 levels were found to be lower in rural females (β = −0.12, P = 0.030) and urban males (β: 0.11, P < 0.001) compared to their respective contemporaries. Conclusions Vitamin B12 deficiency was higher among rural school‐going adolescents. Boys had a higher B12 deficiency than girls. Inverse associations of serum B12 with adiposity indices were observed. Serum B12 levels were positively associated with dietary vitamin B12 intake.

Purpose This paper aims to explore knowledge management (KM) literature to understand the relationships among different KM practices and organizational performance (OP) in terms of the four balanced scorecard (BSC) outcomes, i.e. learning and growth, internal process, customer satisfaction and financial performance, as a measure of OP. Design/methodology/approach A systematic review of peer-reviewed journal articles has been carried out of theoretical and empirical articles to understand the linkages between KM practices and OP, accessed mainly through sources, such as ProQuest, EBSCO host, Google Scholar and other e-databases. Measures of OP have also been extracted from the literature and grouped under the four BSC outcomes to gauge the gravity of the effect. An integrated conceptual framework helps to explore the relationship between the said variables. Findings This study provides a conceptual model of the effect of various KM practices on different aspects of OP measured through BSC. It contributes to organizations by helping them understand the importance of integration of the KM efforts to obtain desirable results. It will, for the first time, put the entire organization in perspective and help managers draw a bigger picture to understand the overall effect of KM practices. Research limitations/implications First, the KM practices shortlisted for this research are extensive but the list may not be exhaustive. Second, the model is not empirically proved. Findings of the study would help in creating a roadmap to enhance performance by a successful implementation of KM practices. Originality/value This paper contributes to KM literature by adding the fact that KM practices not only affect learning and growth perspective of an organization but also have far-reaching effects on OP in terms of customer service perspective, internal process perspective and financial perspective.

Background: Thyroid hormones are major regulators of energy metabolism and increased levels of the hormones (hyperthyroidism) results in an increase in the metabolic rate. Thyroid dysfunction causing alteration in hormone secretion leads to perturbations in the metabolic status. The hypermetabolic state may cause increased generation of reactive oxygen species (ROS), leading to oxidative stress in these patients. This study was carried out to verify our proposition by measuring the ROS in the terminally differentiated cells like the peripheral blood mononuclear cells of the patients.Methods: Flow-cytometric analysis of the ROS was carried out using 2 0 ,7 0 dichlorofluorescein diacetate in the isolated peripheral blood mononuclear cells of the subjects.Results: ROS generation was found to be 3-folds higher in hyperthyroids as compared with euthyroids and hypothyroids and this was not found to be gender specific.Conclusions: Hyperthyroidism results in ROS generation in patients, which can be detected flow cytometrically in the peripheral blood mononuclear cells. Hence, this could complement the other thyroid function tests facilitating the diagnosis and design of appropriate therapy. q 2005 International Society for Analytical Cytology