Abstract

Bombay blood group is the rarest blood group in the world. It is a blood group which shows absence of A,B,H antigens on red cells and presence of anti- A, anti-B and potent wide thermal range anti-H antibodies in serum reacting with all O blood group. Dr. Y.M. Bhende first discovered Bombay blood group in 1952 at Bombay in India now known as Mumbai. This is the reason why this blood group got the name Bombay blood group. DOI: http://dx.doi.org/10.3329/bjmed.v22i1.13596 Bangladesh J Medicine 2011; 22: 21-23

Context: Most deaths caused by transfusion worldwide is due to transmission of infectious agents like Virus, Bacteria and Protozoa. The risk of disease transmission increases many fold if blood donor selection is inappropriate (such as blood from professional donor) and testing of all blood for transfusion is inadequate. Methods: The study was carried out in transfusion Medicine department of Dhaka Medical College Hospital from January to December 2009 to see the prevalence of HBV, HCV, HIV, Treponema pallidum and Malarial parasite among the donor. Results: The study was carried out on 21448 donors, among whom 4464 (20.81%) were voluntary and 16984 (79.19%) were relative donors. Among 21448 donors, 21081 (98.29%) were selected and 367 (1.71%) were rejected. Out of 21081 selected donors 4406 (20.9%) were voluntary donor and 16675 (79.1%) were relative donor. Out of 367 rejected 58 (15.8%) were voluntary and 309 (84.2%) were relative donor. On analyzing the 367 rejected cases, HBsAg positive 297 (80.93%), Anti HCV positive 38 (10.35%), Malarial Parasite positive 23 (6.27%), Treponema pallidum positive 9 (2.45%) and none found positive for HIV. Key words: Blood donor; Voluntary donor; Relative donor; Screening. DOI: 10.3329/jdmc.v19i1.6245 J Dhaka Med Coll. 2010; 19(1) : 16-18.

DOI: http://dx.doi.org/10.3329/jdmc.v21i1.13236 J. Dhaka Med. Coll. 2012; 21(1): 37-40

Introduction: Without blood there may be no blood transfusion. Without donors there may not any blood. During vasovagal reaction there is chance of accidental fall and injury to blood donor. So improving the safety of the blood donation experience will reduce the donor injuries and increase the blood donation, donation frequency and donor satisfaction. Objective: This study was done to find out the incidence of blood donor reaction- vasovagal reactions among the blood donors attending at transfusion medicine department of Dhaka Medical College Hospital and to improve the donor’s safety. Methodology: This study was done at Transfusion Medicine Department of Dhaka Medical College Hospital in the period between January 2010 to December 2010. Total 21815 donors of 18 to 55 years of both sexes were selected after reviewing the questionnaire, physical and medical examination and written consent. Donors were observed for 30 minutes after donation. The needle site was covered with a bandage and the donor was directed to keep the bandage on for several hours. Result: In this study, out of 21815 donors 163(8.7%) developed reaction. In163 reactions, 72(44.18%) were in male and 91 (55.82%) were in female donors. Within 20179 male donors, adverse reactions occurred in 72 (0.35%) and within 1636 female donors, adverse reactions occurred in 91 (5.56%) The symptoms were agitation 23 (14.12%), pallor 31 (19.02%), sweating 29 (17.79%), nausea 21 (12.88%), vomiting 38 (23.21%), cold feeling 12(7.36%), loss of consciousness 9(5.52%),i.e. severe reactions were 9(5.53%) and mild to moderate reactions were154 (94.47%). Among the reactions 127 (0.89%) occurred in new donors, 32 (0.49%) occurred in occasional donors and 4 (0.37%) in periodic donors. Conclusion: Vasovagal reactions are more common in female and new donors. DOI: http://dx.doi.org/10.3329/bjmed.v22i2.13589 Bangladesh J Medicine 2011; 22: 47-50