The duplication-degeneration-complementation (DDC) model predicts that subfunctionalization of duplicated genes is a common mechanism for their preservation. The additional Hox complexes of teleost fish constitute a good system in which to test this hypothesis. Zebrafish have two hoxb complexes, with two hoxb5 genes, hoxb5a and hoxb5b, the expression patterns of which suggest subfunctionalization of an ancestral hoxb5 gene. We characterized conserved non-coding elements (CNEs) near the zebrafish hoxb5 genes. One CNE, J3, is only retained in the hoxb5a locus, whereas the others, J1 and J2, are present in both hoxb5 loci. When tested individually, the enhancer activity of individual CNEs, including J3, extensively overlapped and did not support a role in subfunctionalization. By contrast, reporter transgene constructs encompassing multiple CNEs were able to target reporter gene expression to unique domains of hoxb5a and hoxb5b expression. The deletion of J3 from the hoxb5a locus resulted in expression that approached that of hoxb5b, whereas its insertion in the hoxb5b locus increased reporter expression and rendered it more similar to that of hoxb5a. Our results highlight the importance of interactions between CNEs in the execution of complementary subfunctions of duplicated genes.
This article aims to explain the lethal violence against women observed in certain contexts in recent years. It analyses the phenomenon of female homicide victimization through the lens of Pierre Bourdieu’s theory of symbolic violence. The principal manifestation of homicide of female victims explored in this article are honour killings in migrant communities in Europe, a culturally specific form of gender-related homicide. The concept of symbolic violence partially explains the honour-related violence within the framework of patriarchal theories and emphasizes the function of direct violence against women as a patriarchal backlash in a situation of structural changes in gender relations. Applying Bourdieu’s theory to honour killings in Europe will explain the dynamics of violence against women in a situation where symbolic patriarchal power is undermined, due to new structural conditions, and offer guidelines on context and agent-focused approaches to tackling the phenomenon.
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It is interesting to observe how penal populism intersects with feminism when it comes to gender-based violence, as regards both anti-rape and domestic abuse reforms. There is a vast scholarship (Bumiller, 2008; Gottschalk, 2006; Gruber, 2007) in the US explaining how feminist activism turned to state power to demand more protection and more criminalization, and little focus on the European context. This article aims to analyse the development of what might be called feminist penal populist discourse in Spain and Poland. Whereas penal populist discourse has been conspicuous in Spain, and the authorities there ally themselves with domestic feminist groups and scholars to combat gender-based violence, Poland has never embraced the feminist agenda, despite the widespread influence and effectiveness of penal populism in that country. The article attempts to answer the general question: Why are feminist demands likely to be addressed in some countries where penal populism discourse has emerged in the political and public sphere, but not in others? The analysis demonstrates that the proclivity for penal populism and selection of topics are strongly related not only to some structural factors or political culture, but also to the historical and social context of each country. In Spain, the feminist movement was incorporated and politicized by left-wing parties into mainstream politics, whereas in Poland there was no grass-roots movement for women’s liberation for a long time, and the emancipatory politics during the communist era was superficial.
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