Antagonistic medication response (ADR) can be characterized as any toxic change which is suspected to be because of a medication, happens at dosages ordinarily utilized in man, requires treatment or decline in portion or shows alert later on the utilization of similar medication. Escitalopram is a medication which goes under the classification of particular serotonin reuptake inhibitors (SSRIs) (antidepressants). It is the S-enantiomer of the racemic subsidiary of citalopram, which specifically restrains the reuptake of serotonin with practically no impact on norepinephrine or dopamine reuptake. Practically all the antidepressants and antipsychotics have been connected to QT prolongation. In a patient with previously diagnosed congenital QTS, we present a drug-induced QT extension owing to the escitalopram overdose. A 15-year-old Caucasian woman was presented with an escalopram overdose after a suicide attempt. The patient has a lengthy QT period of torsade de point incidents. The patient was received and monitored in the telemetry facility. She proceeded to exhibit the persistently extended QT period after the resolution of torsades de punes. She was diagnosed with a congenital QT condition by the cardiology clinic. In this situation, an escitalopram overdose is seen to trigger an immediate QT extension for a patient who has congenital LQTS and the value of an electrocardiogram before SSRIs are started, particularly for those at high risk of QT prolongation.

Diabetes mellitus (DM) is a assorted collection of Metabolic issue described by hyperglycemia. It may be connected with abnormalities in carbohydrate, fat, also protein digestion system and might bring about Ceaseless difficulties including microvascular, microvascular and neuropathic issue. Patient Counseling is a key component of Patient Care. Objective: The detached investigation on the patient demographic particulars and evaluate the patient’s Knowledge, Attitude & Practice and Quality of Life amid select Diabetic Patients and to improve them by providing Patient Counseling. Materials & Methods: An Observational study was carried out at a tertiary care hospital in Krishnagiri, Tamil Nadu by phase of 6 months. 52 patients were included in the investigation created on presence and segregation criteria. Knowledge, Attitude & Practice and Quality of Life is evaluated using validated Questionnaires and the score thus obtained before counseling was compared with the corresponding score obtained after counseling. Consequences: by conclusion of the learning, there was a important improvement in the Knowledge, Attitude & Practice (KAP) and Quality of Life (QoL) between the patients (p<0.05). Conclusion: We conclude that Patient counseling is a key part of Diabetic care. Patient Counseling stressing the importance of lifestyle Management, Drug therapy and knowledge of the disease can improve Quality of Life and prevent further Complications.