A new naturally occurring N 1 , N 6-dihydrocinnamyl putrescine bisamide, JBIR-94, along with nine structural analogs and a series of substituted phenyl and alkyl putrescine bisamides have been synthesized from putrescine and appropriately substituted carboxylic acids, through carboxylic acid chlorides. Antimicrobial, 5-Lipooxygenase enzyme inhibitory and antioxidant studies were performed for all synthesized compounds. Dihydrocinnamyl series of putrescine bisamides (4a-4i) showed good bioactivities compared to substituted phenyl (6a-6g) and diakyl (6h-6j) series of compounds. Among all compounds, 4h (methylenedioxy analog) and 4a (JBIR-94) showed good antimicrobial, antiinflammatory and antioxidant activities.

General experimental procedure for the synthesis of 3,5disubstituted 1,2,4-oxadiazoles (5a-5n) 3 3 Synthesis of 3,5-disubstituted 1,2 4-oxadiazoles and characterization data (5a-5n) 4 4 1 H, 13 C NMR spectra of new compounds 16 5 References 28

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PTSA Catalyzed Straightforward Protocol for the Synthesis of 2-(N-Acyl)aminobenzimidazoles and 2-(N-Acyl)aminobenzothiazoles in PEG. -(VIDAVALUR*, S.; GAJULA, M. B.; TADIKONDA, R.; NAKKA, M.; DEGA, S.; YADAV, S. K.; VOOSALA, C.; Tetrahedron Lett. 55 (2014) 16, 2691-2694, http://dx.

Efficient and Convenient Protocol for the Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazoles Using HClO 4-SiO2 as a Heterogeneous Recyclable Catalyst. -The protocol uses amidoximes (I) and acid anhydrides (II) as starting materials and provides the corresponding products (III) in good to excellent yields. -(TADIKONDA, R.; NAKKA, M.; GAJULA, M. B.; RAYAVARAPU, S.; GOLLAMUDI, P. R.; VIDAVALUR*, S.; Synth. Commun. 44 (2014) 13, 1978-1986, http://dx.