Background: Enuresis is one of the most common problems in children with physical and psychological complications that can disturb their social relationships. The main objective of this study is to evaluate the relationship between enuresis and its associated etiologies in children aged 5 to 15 years in Zahedan. The study further contributes to an early realization of the parents of children with enuresis-associated problems. Methods: Following a descriptive design, 200 children (5 to 15 years old) suffering from enuresis referred to nephrology and psychiatric clinics in Zahedan in 2019 were recruited. Data were analyzed using SPSS software. Results: Of 200 children with enuresis, 134 (67%) were girls, and 66 (33%) were boys. Also, 174 (87%) were aged 5 - 10 years, and only 26 (13%) were 10 to 15 years old. Birth weight of 172 (86%) children was 2500 - 4000 g, 20 (10%) were < 2500g, and only 8 (4%) were > 4000 g. Fecal incontinence was observed in 99 cases (49%), and 101 (51%) did not have fecal incontinence. Attention deficit hyperactivity disorder (ADHD) was found in 80 (40%) cases. For 144 (72%) children, we found no stress, and 56 children (28%) had stress. Urinary tract infection was observed in 142 children (71%). According to imaging studies, 34 children (17%) with enuresis had congenital kidney abnormalities and 166 (83%) had no kidney problems. Conclusions: The significant etiologies typically found in the onset of enuresis and its exacerbation can be controlled or treated. Since the complications of enuresis have not been properly clarified for families, it is of crucial importance to increase awareness about this health problem.
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