An advanced mode of drug delivery system has been developed to overcome the major drawbacks associated with conventional drug delivery systems. This review gives a detailed idea about a nanoemulsion system. Nanoemulsions are nano-sized emulsions, which are manufactured for improving the delivery of active pharmaceutical ingredients. These are the thermodynamically stable isotropic system in which two immiscible liquids are mixed to form a single phase by means of an emulsifying agent, i.e., surfactant and co-surfactant. The droplet size of nanoemulsion falls typically in the range 20-200 nm. Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as ultrafine dispersions whose differential drug loading; viscoelastic as well as visual properties can cater to a wide range of functionalities including drug delivery. However there is still relatively narrow in sight regarding development, manufacturing, fabrication and manipulation of nanoemulsions which primarily stems from the fact that conventional aspects of emulsion formation and stabilization only partially apply to nanoemulsions. This general deficiency sets up the premise for current review. We attempt to explore varying intricacies, excipients, manufacturing techniques and their underlying principles, production conditions, structural dynamics, prevalent destabilization mechanisms, and drug delivery applications of nanoemulsions to spike interest of those contemplating a foray in this field.
The Oral fast dissolving drug delivery system is defined as dissolved or disintegration in few seconds or within a few minutes hold in the mouth without water and swallowing. In recent years oral fast dissolving films is promising drug delivery system due to several advantages for pediatric and geriatric patient who have trouble to swallowing conventional oral dosage types. over few decades fast disintegrating tablets have gained significant attention alternative to conventional tablet and capsule due to good patient compliance FDTs are solid dosage form which is rapidly disintegrate usually in seconds or minutes when placed on the tongue but there are still some changes due to chocking. Oral fast dissolving films is another way to solve this issue, as oral strips have been novel for the past few years and are well accepted by customers for distribution. Nowadays, breath strips, supplements and a variety of personal care items are commonly used by consumers. This review consists of updates on methods, ingredients and different technology used in fast dissolving film.
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