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Objective: COVID-19 prevalence is a new and serious threat to public health. The disease has had an impact on nearly every important economic, political, social, and even military aspect of many countries around the world. As a result, the psychological effects of this viral disease on different levels of society's psychological health are critical, necessitating scientific research. This study looked into the possible link between COVID-19 and psychological distress and anxiety in Iran. Methods:The first large-scale global study of psychological distress and anxiety in public society, this crosssectional (descriptive-analytical) study was based on the participation of people from some Asian countries during the COVID-19 epidemic. Only the results from Iran were presented in this article. This study had 1480 participants and used a standard questionnaire called the COVID-19 Peritraumatic Distress Index (CPDI) with a Cronbach's alpha of 0.82. Results:It was discovered that 1171 (79%) of the participants were female, while 309 (21%) were male. The CPDI Questionnaire yielded a mean score of 54.16±6.13. There was a significant relationship (p=0.0002) between age group and total score of psychological distress and anxiety. The findings revealed a link between anxiety variables and education (p = 0.0001), monthly income (p = 0.008), and gender (p = 0.019). Conclusion:It can be concluded that many study participants were in an unfavorable psychological distress and anxiety situation.

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