Synchronization plays an essential role in processing information and decisions by neurons and their networks in the brain, and it is useful to study the synchronization of neuron networks, as a part of the process of understanding the functionality of both healthy and diseased brains. In the past, most studies had developed control schemes relating to synchronization problems which were limited to two or three neurons, which cannot depict the dynamic synchronization behavior of neuron networks. In this paper, we investigated the synchronization issues associated with a ring-structured network of FitzHugh-Nagumo (FHN) neurons, under external electrical stimulation, and with single-and dual-state gap junctions. In addition, the gap junctions (coupling)s and ionic gate disturbances were included in the dynamics of this FHN neuronal network, making our work both more realistic, and more challenging. Thus, each neuron in this network was influenced synaptically by its neighboring two neurons. A simple, robust, and adaptive control scheme, for both a single-and the dual-gap-junction network has been proposed, which will compensate for the nonlinear dynamics without direct cancelation to achieve synchronization. Sufficient conditions to guarantee synchronization of both membrane potentials and recovery variables were derived by using Lyapunov stability theory. Finally, the proposed scheme was validated, and its efficacy was comprehensively analyzed through numerical simulations.
Synchronization plays a significant role in information transfer and decision-making by neurons and brain neural networks. The development of control strategies for synchronizing a network of chaotic neurons with time delays, different direction-dependent coupling (unidirectional and bidirectional), and noise, particularly under external disturbances, is an essential and very challenging task. Researchers have extensively studied the synchronization mechanism of two coupled time-delayed neurons with bidirectional coupling and without incorporating the effect of noise, but not for time-delayed neural networks. To overcome these limitations, this study investigates the synchronization problem in a network of coupled FitzHugh–Nagumo (FHN) neurons by incorporating time delays, different direction-dependent coupling (unidirectional and bidirectional), noise, and ionic and external disturbances in the mathematical models. More specifically, this study investigates the synchronization of time-delayed unidirectional and bidirectional ring-structured FHN neuronal systems with and without external noise. Different gap junctions and delay parameters are used to incorporate time-delay dynamics in both neuronal networks. We also investigate the influence of the time delays between connected neurons on synchronization conditions. Further, to ensure the synchronization of the time-delayed FHN neuronal networks, different adaptive control laws are proposed for both unidirectional and bidirectional neuronal networks. In addition, necessary and sufficient conditions to achieve synchronization are provided by employing the Lyapunov stability theory. The results of numerical simulations conducted for different-sized multiple networks of time-delayed FHN neurons verify the effectiveness of the proposed adaptive control schemes.
The mathematical modeling of malaria disease has a crucial role in understanding the insights of the transmission dynamics and corresponding appropriate prevention strategies. In this study, a novel nonlinear mathematical model for malaria disease has been proposed. To prevent the disease, we divided the infected population into two groups, unaware and aware infected individuals. The growth rate of awareness programs impacting the population is assumed to be proportional to the unaware infected individuals. It is further assumed that, due to the effect of awareness campaign, the aware infected individuals avoid contact with mosquitoes. The positivity and the boundedness of solutions have been derived through the completing differential process. Local and global stability analysis of disease-free equilibrium has been investigated via basic reproductive number R0, if R0 < 1, the system is stable otherwise unstable. The existence of the unique endemic equilibrium has been also determined under certain conditions. The solution to the proposed model is derived through an iterative numerical technique, the Runge–Kutta method. The proposed model is simulated for different numeric values of the population of humans and anopheles in each class. The results show that a significant increase in the population of susceptible humans is achieved in addition to the decrease in the population of the infected mosquitoes.
Power supply is the cornerstone for the sustainable socio-economic development of any country. In a developing country like Pakistan, shortage of power supply is the main obstacle to its economic growth, making it a disputed and contested resource among different administrative units/provinces and socio-economic sectors. A key challenge is allocating the limited available power among provinces with conflicting and competing needs amid the supply-demand gap. In this research, the allocation of energy during a shortage is considered as a game-theoretic bankruptcy problem. Five bankruptcy rules namely the Proportional Rule, Constraint Equal Award Rule, Constraint Equal Loss Rule, Talmud Rule and Piniles Rule are used for power allocation among the provinces of Pakistan. Each province is characterized by its power demand. A new framework is also proposed for power allocation, which synthesizes the Nash bargaining solution concept with bankruptcy theory to resolve power-related disputes among the four provinces within Pakistan. Additionally, a new method is introduced in this study to compare and contrast the different allocation rules. The results suggest that the basic power demands of the provinces can be satisfied by the proposed disagreement points among the provinces, and the bargaining weights can highlight the role of different levels of power claims, lengths of transmission lines, and variations in population among provinces. The findings also suggest that, due to the lowest dispersion, the proportionate rule is the most suitable method for power allocation among the provinces. The paper combines relevant bankruptcy rules with Nash bargaining theory to propose an algorithm for addressing power sector supply-demand mismatches in Pakistan.
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