This research aimed to study the antibacterial activity and Antibiotic effect of hot aqueous extract of leaves of Ziziphus spina Christy (Sidr),against clinical isolate of Staphylococcus wernari. four isolates were initially diagnosed as Staphylococci bacteria, then one isolation was chosen depending on its sensitivity and resistance to several different types of antibiotics. The VITEK-2 compact system (ID and AST) and PCR were used to confirm the type of staphylococcal isolates . The results showed that one isolate was due to Staphylococcus wernari. the ability of isolate to form biofilm was tested using the Microtiter plate method (96 wells). The results indicated that the extracted isolate was able to produce a biofilm. Where there was a clear effect of moxifloxacin and penicillin G with (MIC), (Sub-MIC) and (Sub-MIC) in inhibiting the growth of bacteria, A significant (P < 0.001).Synergistic effect between Penicillin G, Moxifloxacin with (MIC), (Sub-MIC) and (Sub-MIC) were tested with hot aqueous extract of Ziziphus spina christi (Sidr) leaves with 50 mg/mL. The results showed a high synergy between two types of antibiotics and plant extracts.
Background and Objectives: Diabetes mellitus (DM) is a group of metabolic disorders of carbohydrate metabolism in which glucose is underutilized, producing hyperglycemia. Furthermore, it is proposed that the underutilization of glucose is associated with changes in the lipid profile. Changes in lipid profiles are also well related to the severity of DM. This study involved 50 were patients admitted with a diagnosis of DM; blood samples were drawn under aseptic precautions from cases of DM and healthy controls. Necessary investigations were carried out and values were tabulated for cases and controls separately for statistical evaluation. Our Results show that the DM patients compared to controls significant increase in the following parameters were observed. Cholesterol ratios increased. Furthermore, the levels of triacylglycerol increased. We conclude that there is a statistically significant large effect in cholesterol and TG a level of cases compared with controls, cholesterol level is increased and TG levels were well associated with blood sugar also increased .
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