Introduction: Diabetes mellitus is one of the leading cause of mortality and morbidity worldwide. Type 2 DM is a complex group of disorders characterized by different levels of insulin resistance, impaired secretion of insulin , and increased production of glucose. The complications of diabetes mellitus are inuenced by the average level of blood glucose along with glycosylated hemoglobin. Serum ferritin is an indicator of iron store. Iron stores are associated with decrease in insulin sensitivity, insulin secretion and hence type 2 diabetes. Methods: This study was done in Department of Biochemistry in collaboration with Medicine Department of Gandhi medical college Bhopal. 160 previously diagnosed type 2 diabetes subjects (mean age 55.59±7.74 years) with mean BMI 30.14±3.48kg/m2 were taken and their Serum ferritin, Fasting Blood Sugar and Glycosylated Hemoglobin were measured. Results: It was found that serum ferritin was signicantly high in diabetic patients and serum ferritin had a positive correlation with increasing glycosylated hemoglobin and Fasting blood sugar. Conclusion:It was concluded that serum ferritin level can be used as an indicator of control of glycaemia in type 2 diabetes mellitus patients. HbA1C and Serum ferritin level can also be used as a marker to prevent complications of the disease.
Objectives: (1) The objective of the study was to evaluate and compare the levels of ferritin, iron, total iron binding capacity (TIBC), and hemoglobin (Hb) in cases and controls (2) and to correlate these parameters with the severity of psoriasis. Methods: Iron-profile including serum ferritin, iron, TIBC, and Hb was evaluated in 100 subjects, 50 cases (psoriatic) and 50 controls (normal healthy individuals). A preformed pro forma was filled for each patient after taking written consent. Ferritin was evaluated using fully automated chemistry analyzer, iron, and TIBC were evaluated by semi-autoanalyzer and Hb by Automated Hematology Cell Counter. Results: In our study, a lower level of serum ferritin, iron, and Hb was found in cases than controls, whereas the levels of TIBC were found higher in cases than controls. (p<0.05) We found a negative correlation of ferritin and a positive correlation of hemoglobin with psoriasis area and severity index. Conclusion: We conclude that iron profile should be done early in the course of disease to improve dietary advices and treatment modalities.
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