Background: Neutrophil lymphocyte is an indicator of subclinical inflammation. Type 2 diabetes mellitus is associated with chronic low-grade inflammation. One of the novel inflammatory markers is hemogram derived neutrophil to lymphocyte ratio. There are very few studies which are directly accessing the relation between NLR and HbA1c, so in the present study our aim to correlate neutrophil lymphocyte ratio with glycemic control in patients having type 2 diabetes.Methods: Hospital based observational cross section study was carried out at department of medicine, Pt JNMMC and Dr BRAM Hospital, Raipur, between September 2018 to August 2019. 105 patients with type 2 diabetes mellitus according to ADA criteria who were aged more than 18 years were included in the study. Relevant investigation and complete blood count were performed. Microsoft excel and SPSS version 25 were used for collection and analysis of the data, p<0.05 was considered as significant.Results: Out of 105 patients who were given the consent for the study, the ration of male is to female was 1:0.98, mean age of all the patients was 51.77±10.56 years, mean neutrophil lymphocyte ratio among the patients was 6.30±2.646, HbA1c count more than ≥9 was 54 (51.27%). NLR had a positive correlation with HbA1c and was found to be an independent predictor of poor glycemic control in patients with type 2 diabetes mellitus.Conclusions: Increased NLR is associated with elevated HbA1c and poor glycemic control. Type NLR should be used as a marker of diabetic control level in addition to HbA1c in type 2 diabetic subjects.

Background: The study aimed to assess the magnitude of asthma chronic obstructive pulmonary disease asthma chronic obstructive (ACO) in patients with chronic airway disease.Methods: The study was conducted as cross-sectional study on patients with chronic airway disease presenting at our institute during the study period of 1 year. Global initiative for asthma management and prevention (GINA) syndromic approach table was used to diagnose patients with chronic airways disease. Syndromic and confirmatory diagnosis of ACO was made based upon clinical features and spirometry respectively.Results: About 73.6% were diagnosed as chronic obstructive pulmonary disease (COPD) and 26.4% cases were diagnosed as asthma. Overall ACO was present in 20% cases. ACO was significantly associated with advancing age, male gender, and longer duration of smoking (p<0.05) in asthma patients whereas in COPD patients ACO was associated with advancing age (p<0.05).Conclusions: Overall one fifth of the patients with chronic airway disease have asthma COPD overlap. The ACO is observed in almost equal proportions in asthma and COPD. ACO prevalence was found to increase with age in patients with asthma and COPD.

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