Association of tissue eosinophilia with oral squamous cell carcinoma has shown variable results ranging from favourable to unfavourable or even having no influence on prognosis. Also, very few studies have been done to know the role of eosinophils in premalignancy. So the present study investigated role of eosinophilic infiltration in oral precancer and cancer and its possible use as a prognosticator. 60 histopathologically proven cases (20 cases each of metastatic and nonmetastatic oral squamous cell carcinoma and oral leukoplakia with dysplasia of various grades) were included. Congo red is used as a special stain for eosinophils. Each specimen slide was viewed under high power in 10 consecutive microscopic fields for counting of eosinophils. As a result, a significant increase in eosinophil count was found in oral carcinomas compared to dysplasia. Nonmetastatic cases showed higher counts than metastatic carcinomas. So, it is concluded that eosinophilia is a favourable histopathological prognostic factor in oral cancer. Moreover, higher eosinophil counts in carcinoma group compared to dysplasia group proved that they might have a role in stromal invasion thus suggesting that quantitative assessment of tissue eosinophilia should become a part of the routine histopathological diagnosis for oral precancer and OSCC.

Osteomas are benign, slow-growing osteogenic tumours rarely occurring in the craniofacial bones. Osteomas are characterised by the proliferation of compact and/or cancellous bone. It can be of a central, peripheral, or extra skeletal type. The peripheral type arises from the periosteum and is rarely seen in the mandible. The lingual surface and lower border of the body are the most common locations of these lesions. They are usually asymptomatic and can be discovered in routine clinical and radiographic examination. In this paper, the authors present a large solitary peripheral osteoma located in the inferior surface of the left angle of mandible and causing facial deformity in a 14-year-old boy. Radiographic examination by diagnostic radiographs revealed mixed appearance (radiopaque- radiolucent), well-circumscribed, pedunculated mass approximately 3.5 cm in size. The osteoma was removed surgically, and no recurrence has been observed.

Odontogenic anomalies of teeth can be encountered frequently in dental practice. Fusion and gemination are developmental anomalies leading to eruption of joined elements as double teeth. These anomalies pose a challenge even to the most experienced clinician in treating these teeth. This article highlights the importance of clinical and radiographic correlation in arriving a definitive diagnosis.

Background and Aims:Myofibroblasts are one of the important components of the tumor microenvironment which could possibly play an important role in tumor progression. The purpose of this study was to compare the presence of α-smooth muscle actin (α-SMA) and CD34 positive fibroblasts in nonmetastatic and metastatic oral squamous cell carcinoma and to evaluate their role in tumor metastasis.Materials and Methods:Ten cases each of histologically proven metastatic and nonmetastatic oral squamous cell carcinoma formed the study group. The tissue sections were stained immunohistochemically for α-SMA and CD34. The stromal spindle cells positive for these markers in the study groups were counted and compared.Results:α-SMA positive cases were more in the metastatic group and CD34 positive cases were found to be more in the nonmetastatic tumors.Conclusions:Though difference in the staining pattern was statistically nonsignificant, the inverse relationship between α-SMA and CD34 positive cells is indicative of dynamic nature and the influence of tumor stroma in tumor progression and metastasis.

Results clearly showed that orthodontic appliances increase colonization of S. mutans and Candida albicans in oral cavity over the period of treatment time which can be controlled with proper timely brushing. The study also concludes superiority of electronic tooth brushing over manual tooth brushing.