Background: ABO blood groups are the primary, most common, conspicuous, and easily detectable groups. These blood group specific antigens are not the exclusive domain of the erythrocyte, but abundantly present in many other bodily secretions such as sweat, semen and even saliva. Absorption inhibition and absorption elution are the main methods to detect salivary blood group antigens. The aim of this study is to detect the secretor status of 100 samples of saliva and to compare the diagnostic efficacy of absorption elution method and absorption inhibition methods in detecting the ABO (H) blood group antigens in secretors. Materials and Methods: Totally 100 un-stimulated whole saliva samples were analyzed for the presence of ABO (H) blood group specific antigens by absorption inhibition and absorption elution methods. Initially, secretor status was ascertained by detecting the H antigen in saliva, and both methods were used to detect the blood groups from saliva and the results were compared with that of blood which were statistically analyzed. Results: Of the 100 samples, 77 secretors and 23 non-secretors. Using absorption inhibition method 62 out of 77 samples gave results that matched with blood. Using absorption elution 70 out of 77 samples gave matching results. Absorption elution depicted better sensitivity, more true positive matches with blood as well as a higher Kappa coefficient. Conclusion: Absorption elution gave better results than absorption inhibition.

Background: Diabetes mellitus is a serious and leading health problem worldwide and is associated with severe acute and chronic complications that negatively influence both the quality of life and survival of affected persons. Growing epidemiologic evidence suggests that people with diabetes are at significantly greater risk for cancer in general and recent studies also demonstrated that glucose intolerance was associated with a higher risk of oral cancer death, beginning in the prediabetic range of glucose intolerance. Aim:We undertook this study with the aim of finding out an association between impaired glucose tolerance and oral cancer along with finding out prevalence of other risk factors for oral cancer. Subjects and Methods:45 cases and 45 controls were selected for the study. Oral glucose tolerance was performed on subjects who satisfied inclusion criteria and were willing to sign informed consent form. Results and Conclusion:Fifty three percent of the cases had abnormal glucose tolerance as compared to Thirty one percent of the controls. It was statistically significant with a p value of 0.032. To conclude, hyperglycemia (which includes IFG, IGT and diabetes) increase the risk of oral cancer two folds, however Impaired Glucose tolerance alone as defined by ADA does not appear to play a role.

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