The value added from dynamic downscaling in climate projections of extratropical cyclones over the southwestern South Atlantic Ocean (SAO) is evaluated. For this purpose, the Regional Climate Model version 4 (RegCM4) is nested in the Hadley Global Environment Model 2 ‐ Earth System (HadGEM2‐ES) global climate model under the RCP8.5 scenario. The analyses focus on three time slices: the present (1979–2005), near future (NF: 2020–2050) and far future (FF: 2070–2098) climates. The cyclone tracking used an algorithm that searches for minima of relative vorticity at 925 hPa. Simulations of the present climate are compared to data from an ensemble of five reanalyses (ERA‐40, ERA‐Interim, NCEP‐NCAR, NCEP‐DOE and CFSR). For present climate, there is good agreement among reanalyses and models in associating austral winter and summer with higher and lower cyclone frequency, respectively. In addition, the simulations present the mean features of the cyclones (lifetime, distance travelled and mean velocity) as similar to those of the reanalysis. Moreover, RegCM4 outperforms the HadGEM2‐ES by simulating more realistically the spatial pattern of the cyclogenesis density over the SAO, which indicates value added from the RegCM4 downscaling. For the future climates, a decrease is projected for the annual frequency of cyclones, which reaches −6.5% (−3.6%) in RegCM4 (HadGEM2‐ES) in the NF and −11.4% (−10.4%) in the FF. Future projections do not indicate changes in the mean intensity of the cyclones. The negative trend of the cyclone frequency affects the precipitation. For FF, a decrease of approximately 15% in the precipitation associated with cyclones is projected.

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Undernutrition is a worldwide problem affecting millions of unborn and young children during the most vulnerable stages of brain development. Total restriction of protein during the perinatal period of life can alter the development of the mammalian fetus and have marked repercussions on development of the central nervous system (CNS). The brain is vulnerable to undernutrition with altered morphologic and biochemical maturation, leading to impaired functions. The focus of this study is to investigate [U-¹⁴C]glycine metabolism in undernourished rats submitted to pre- and postnatal protein deprivation (diet: 8% protein with and without addition of L-methionine; control group: 25% protein). Although undernutrition produced a reduction in cerebellar weight and alterations in the DNA concentration, the present study shows that glycine metabolism in this structure is partially protected because the undernourished group with L-methionine did not show modifications in glycine metabolism at all ages studied. However, L-methionine deficiency alters glycine metabolism at 7 and 21 days, but in the adult age both undernourished groups presented no differences in oxidation to CO₂, conversion to lipids and incorporation into protein from glycine, compared to the control group.