Objectives. The aim of the study was to compare diabetes control and obstetrical outcomes in pregnant women with type 1 diabetes treated during pregnancy with either continuous subcutaneous insulin infusion (CSII) or multiple daily insulin injections (MDII). Patients and methods. It was a descriptive, retrospective, observational study of 116 Caucasian pregnant women with type 1 diabetes mellitus. Thirty women were treated during pregnancy with continuous subcutaneous insulin infusion (CSII group) and 86 with multiple daily insulin injections (MDII group). Results. Mean age and body mass index did not differ between groups (p >0.05). Duration of diabetes was longer in CSII than in MDII group, 12.7 ±7.20 vs. 7.71 ±6.13 years, respectively (p = 0.0005). There were no differences between the studied groups in glycated hemoglobin (HbA 1c) levels in the I, II and III trimesters of pregnancy-in CSII group 7.41 ±1.75, 6.57 ±1.09 and 6.46 ±0.87, respectively, in MDII group-7.71 ±2.37, 6.65 ±1.18 and 6.75 ±1.21, respectively (p >0.05). There were no severe hypoglycemia and diabetic coma. Mean duration of pregnancy, rate of premature deliveries, newborn birth weight, incidence of SGA and LGA, and the frequency of neonatal hypoglycemia did not differ between groups (p >0.05). The total malformation rate was 5.13%, including 2 terminated pregnancies and the frequency did not differ between groups (p >0.05). The rate of spontaneous abortions was 16.7% in CSII group and 10.3% in MDII (p >0.05). Conclusions. No apparent relationships between mode of insulin therapy and pregnancy outcome were found in type 1 diabetes patients.

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Analiza wybranych czynników rodzinnych, antropometrycznych i biochemicznych wpływających na masę urodzeniową noworodków kobiet z cukrzycą ciążową

Objectives. The aim of the study was to evaluate an association between the frequency of blood glucose self-monitoring (SMBG) and glycemic control assessed by glycated hemoglobin (HbA 1c) levels. Patients and methods. A group of 600 type 2 diabetic patients aged 63.4 ±9 years (32 to 85 years) and with a mean diabetes duration of 11.4 ±7.7 years (min. 1 year, max. 38 years) were asked to perform weekly blood glucose self-monitoring with an 8-point glucose profile on a chosen day. They were also asked to declare their self-monitoring frequency. HbA 1c levels were measured in all the patients. Results. Most of the patients reported that they performed their SMBG 1-2 times a day (44.3%) or 1-2 times a week (31.8%). All of them measured their blood glucose after an overnight fast and after breakfast. Most patients performed their measurements also after lunch and dinner. Less than 50% of patients did their measurements at night-time. The mean HbA 1c level was 7.45 ±1.08%. Only 20% of patients achieved metabolic control of diabetes recommended by the Polish Diabetic Society (HbA 1c <6.5%). No severe hypoglycemia episodes were obsered. Glycated hemoglobin levels did not differ between the SMBG frequency groups. There was no correlation between HbA 1c levels and the frequency of self-monitoring in any group. Conclusions. There was no correlation between the frequency of SMBG and HbA 1c , which questions the need for multiple daily measurements of blood glucose in all type 2 diabetic patients.