Objectives. The aim of the study was to compare diabetes control and obstetrical outcomes in pregnant women with type 1 diabetes treated during pregnancy with either continuous subcutaneous insulin infusion (CSII) or multiple daily insulin injections (MDII). Patients and methods. It was a descriptive, retrospective, observational study of 116 Caucasian pregnant women with type 1 diabetes mellitus. Thirty women were treated during pregnancy with continuous subcutaneous insulin infusion (CSII group) and 86 with multiple daily insulin injections (MDII group). Results. Mean age and body mass index did not differ between groups (p >0.05). Duration of diabetes was longer in CSII than in MDII group, 12.7 ±7.20 vs. 7.71 ±6.13 years, respectively (p = 0.0005). There were no differences between the studied groups in glycated hemoglobin (HbA 1c) levels in the I, II and III trimesters of pregnancy-in CSII group 7.41 ±1.75, 6.57 ±1.09 and 6.46 ±0.87, respectively, in MDII group-7.71 ±2.37, 6.65 ±1.18 and 6.75 ±1.21, respectively (p >0.05). There were no severe hypoglycemia and diabetic coma. Mean duration of pregnancy, rate of premature deliveries, newborn birth weight, incidence of SGA and LGA, and the frequency of neonatal hypoglycemia did not differ between groups (p >0.05). The total malformation rate was 5.13%, including 2 terminated pregnancies and the frequency did not differ between groups (p >0.05). The rate of spontaneous abortions was 16.7% in CSII group and 10.3% in MDII (p >0.05). Conclusions. No apparent relationships between mode of insulin therapy and pregnancy outcome were found in type 1 diabetes patients.
The paper presents original research, encompassing the results of analyses of modular building façade solutions, as well as innovative design concepts based on these results by students of the Faculty of Architecture at the Poznań University of Technology. Adapting architecture to climate change is the main objective behind research and innovative designs. Reduction of carbon dioxide emissions, thermal comfort of buildings, better thermal environment ergonomics for users of buildings’ interiors, increased energy efficiency together with the use of renewable energy sources are major challenges for today’s designers. Dealing with rainwater, wind and pressure changes are already absolute necessities. Contemporary trends in modern construction in urban areas were identified on the basis of results of analyses of selected existing buildings, presented using tables, graphs and statistical tools. Conclusions from the demonstrated correlations of quantitative data with social, economic and environmental factors became the basis for the students’ conceptual assumptions. The selected innovative façade designs presented in the article demonstrate a variety of solutions for modern modular systems which protect buildings from excessive sun exposure, help insulation resist external factors, generate energy, ventilate buildings, use pressure differences, collect water, purify air, protect fauna, etc. As a result, the developed concepts may be indicative of a contemporary approach to sustainable building design, based not only on reducing any negative environmental impact and conserving natural resources, but also on designing aesthetic buildings based on classic notions of beauty.
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