The objective of this work was to characterize the properties of a synthetic biomaterial composite with nanoparticles size (Blue Bone). This biomaterial is a composite recommended for dental and orthopedic grafting surgery, for guided bone regeneration, including maxillary sinus lift, fresh alveolus filling, and treatment of furcation lesions. The nano biomaterials surface area is from 30% to 50% higher than those with micro dimensions. Another advantage is that the alloplastic biomaterial has homogeneous properties due to the complete manufacturing control. The analyzed biomaterial composite was characterized by XRD, cytochemistry, scanning electron microscopy, porosimetry and in vivo experiments (animals). The results showed that the analyzed biomaterial composite has 78.76% hydroxyapatite [Ca5(PO4)3(OH)] with monoclinic structure, 21.03% β-tricalcium phosphate [β -Ca3(PO4)2] with trigonal structure and 0.19% of CaO with cubic structure, nanoparticles with homogeneous shapes, and nanoporosity. The in vivo experiments showed that the composite has null cytotoxicity, and the site of insertion biomaterials has a high level of vascularization and bone formation. The conclusion is that the synthetic biomaterial with Blue Bone designation presents characteristics suitable for use in grafting surgery applications.

No abstract

Introduction: With the current need for large bone reconstructions due to very robust losses in skeletal architecture, not only of the maxillary and mandibular regions but also in other regions of the body, this guided bone regeneration has been increasingly used. Case Report: A leukoderma patient at 52 years of age sought the implantology clinic of the Brazilian Dental Association (ABO) to solve his case of tooth loss. The patient presented overly aggressive bone loss in the total maxilla, and, because of this, it was planned to reconstruct the lost area with a synthetic particulate nano-biomaterial (Blue Bone, Curitiba, Brazil), with the help of the platelet aggregate (PRF). For the surgery, 6 grams of this biomaterial were used, in the anterior region of the maxilla, tent screws were placed to stabilize the grafted bilateral and maxillary sinus lifting surgeries were performed in the posterior regions. The entire regenerated area was covered with L-PRF membrane for better stability and healing. An incredibly significant gain in bone volume was observed six months after surgery throughout the regenerated region, enabling the placement of dental implants (Systhex, Curitiba, Brazil) and later the placement of the supported prosthesis. Conclusion: The nano graft presented a very favorable result in the gain of bone volume, proving to be an excellent indication for more severe cases of bone loss.

Background: Narrow-diameter implants (3.0-3.5 mm range) have been introduced for the replacement of teeth with insufficient bone structure and/or limited mesiodistal or interimplant spaces, and appear to offer clinical results similar to those obtained with implants of greater diameter. Studies using extra-narrow-diameter implants (2.8 mm) are scarce. Case Presentation: A 59-year-old male patient received two extra-narrow-diameter implants, 2.8 × 11 mm in the region between elements 11 and 14. Together, two 3.5 × 8.5 mm SYSTHEX® platform 4.1 implants were installed in the region of elements 15 and 16 to provide greater stability in the occlusion. Of four previous implants on the maxillary left side, one in the region between the elements 23 and 24 that was located in a very apical position and vestibularized was removed. The provisional was already installed on the elements 11, 21, and 22 with the metal cores already prepared and with the Globteck® implants in the region of the elements 23, 24, and 27. The functional and esthetic results were satisfactory. Conclusions: Insertion of extra-narrow-diameter implants of 2.8 mm in the maxillary anterior region is a reliable option in a patient with absence of elements 12 and 13, restoring masticatory function and aesthetics in the upper arch.