a reduction in the results for the parameters tested in patients of MS is improved by a greater consumption of dietary fiber, such as oat bran. However, additional studies are required to generate clearer recommendations.

EFECTO DE EXTRACTOS CRUDOS DE AJO (Allium sativum) SOBRE EL DESARROLLO in vitro DE Aspergillus parasiticus Y Aspergillus niger. EFFECT OF GARLIC EXTRACTS (Allium sativum) ON THE DEVELOPMENT in vitro OF Aspergillus parasiticus AND Aspergillus niger.

The center of origin and domestication of Physalis spp. is Mexico, where 70 wild species and only two cultivated species are found. Fruits of wild husk tomato are collected by farmers for home consumption or for sale in local markets, where prices are higher than for the cultivated husk tomato. Despite their economic and nutritional importance, they have been little studied. The objective of this study was to determine phytochemical properties, nutritional value, total contents of phenol, anthocyanins and flavonoids, and the antioxidant capacity of the fruits of five wild genotypes of Physalis spp (Quialana, Jalieza, Vigallo, Ejutla and Miahuatlán), collected in the corn harvest season in five localities of Oaxaca, Mexico. The genotypes Quialana and Miahuatlán had the best physical characteristics, but their antioxidant capacity was lower than that of the genotypes Jalieza, Vigallo and Ejutla, which did not exhibit physical characteristics that are attractive for consumers. Moreover, the high contents of phenols and flavonoids, as well as the antioxidant capacity of all the wild genotypes studied, showed that Physalis spp. is an option for more frequent inclusion in the population’s diet. However, because of food globalization issues, production, commercialization and consumption of these wild species is disappearing.

Dyslipidemias are a group of diseases, which are characterized by abnormal blood concentrations of cholesterol, triglycerides and/or low-density lipoprotein-cholesterol (LDL-c). Dyslipidemia is a determinant condition for the progress of an atherosclerotic plaque formation. The resulting atherogenicity is due to at least two mechanisms: first, to the accumulation in the plasma of lipid particles that have the capacity to alter the function of the endothelium and deposit at the atheromatous plaque, and second, at an insufficient concentration of multifactorial type of high density lipoprotein-cholesterol (HDL-c), whose function is to protect against the development of atherosclerosis. Its highest prevalence is encountered among individuals with diabetes, hypertension or overweight. Hyperlipidemia is one of the main predisposing factors for the development of cardiovascular disease. Hyperlipidemia can be the result of a genetic condition, the secondary expression of a primary process or the consequence of exogenous factors (food, cultural, socio-economic, etc.), all of which lead to the elevation of plasma lipid levels. The objective of this study was to carry out an analysis of the genes involved in the development of dyslipidemias that lead to cardiovascular disease with special emphasis on the proprotein convertase subtilin/kexin type 9 (PCSK9) gene. The PCSK9 gene participates in the development of primary dyslipidemias, mainly familial hypercholesterolemia, currently the pharmacological treatment of choice to reduce LDL-c are statins, however, it has been observed that these have been insufficient to eliminate cardiovascular risk, especially in subjects with primary forms of hypercholesterolemia related to genetic mutations, or statin intolerance.