Kidney failure is common in patients with Coronavirus Disease-19 (COVID-19) resulting in increased morbidity and mortality. In an international collaboration, 284 kidney biopsies were evaluated to improve understanding of kidney disease in COVID-19. Diagnoses were compared to five years of 63,575 native biopsies prior to the pandemic and 13,955 allograft biopsies to identify diseases increased in patients with COVID-19. Genotyping for APOL1 G1 and G2 alleles was performed in 107 African American and Hispanic patients. Immunohistochemistry for SARS-CoV-2 was utilized to assess direct viral infection in 273 cases along with clinical information at the time of biopsy. The leading indication for native biopsy was acute kidney injury (45.4%), followed by proteinuria with or without concurrent acute kidney injury (42.6%). There were more African American patients (44.6%) than patients of other ethnicities. The most common diagnosis in native biopsies was collapsing glomerulopathy (25.8%) which associated with high-risk APOL1 genotypes in 91.7% of cases. Compared to the five-year biopsy database, the frequency of myoglobin cast nephropathy and proliferative glomerulonephritis with monoclonal IgG deposits was also increased in patients with COVID-19 (3.3% and 1.7%, respectively), while there was a reduced frequency of chronic conditions (including diabetes mellitus, IgA nephropathy, and arterionephrosclerosis) as the primary diagnosis. In transplants, the leading indication was acute kidney injury (86.4%), for which rejection was the predominant diagnosis (61.4%). Direct SARS-CoV-2 viral infection was not identified. Thus, our multi-center large case series identified kidney diseases that disproportionately affect patients with COVID-19, demonstrated a high frequency of APOL1 high-risk genotypes within this group, with no evidence of direct viral infection within the kidney.

Race/Ethnicity, Attitudes, and Living With ParentsDuring Young Adulthood Non-White young adults are more likely to live with their parents throughout their 20s, more likely to return home after going away to college, and less likely to leave again after returning. Scholars have speculated that subcultural differences in attitudes toward marriage and family play a key role in generating racial/ethnic differences in rates of coresidence with parents among young adults. Data from the National Education Longitudinal Survey of 1988 ( N = 11,228) were analyzed in order to test this hypothesis. Attitudes toward marriage and family were significantly associated with coresidence, especially among young men, but did not substantially account for racial/ethnic differences in living arrangements. Among young non-White women and young Black men, higher rates of coresidence were related to differences from Whites in socioeconomic or marital status (and sometimes both) that were largely independent of differences in attitudes toward marriage and family.A substantial number of young adults live with at least one of their parents. At least 10% of 25-to 34-year-olds, over 3.9 million individuals, lived with a parent or guardian in each year from 1983 through 2011 (U.S.

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Prior research has shown that neighbourhood racial and income contexts remain similar across generations within White, Black and Latino families in the US. This article builds on this research by examining the extent to which geographical mobility during the transition to adulthood attenuates the perpetuation of residential segregation from Whites among Asians, Blacks and Latinos. Data from the National Education Longitudinal Study linked to 1990 and 2000 US census data were analysed. Results suggest that residential exposure to Whites is similar during youth and adulthood among young adults who live in the same metropolitan area where they lived as adolescents, regardless of race/ethnicity. Among those who migrate to another metropolitan area, adolescent exposure predicts exposure among Asian, Black and Latino young adults, but not among Whites themselves. Thus, limited experience with integrated neighbourhoods during adolescence among non-Whites and limited geographical mobility among all young adults help to perpetuate segregation.

Why—and under what conditions—is residential integration positively associated with interethnic friendships between adults in large, diverse metropolitan areas? Both macrostructural and contact theories predict such an association. Yet integrated neighborhoods sometimes resemble “worlds of strangers” (Lofland, 1973), in which much interaction involves fleeting contacts that may increase the salience of stereotypes. Some prior research suggests that a positive association between integration and interethnic friendship may obtain even under such less than ideal circumstances. By analyzing how the association between integration and friendship varies among Anglos, Blacks, and Latinos, this article offers a more nuanced perspective informed by group position theory. Net of selection bias and more intensive forms of intergroup contact, living in an integrated area is only positively associated with having interethnic friendships when integration provides exposure to groups that occupy privileged positions in the larger society's racial–ethnic hierarchy relative to a resident's own group.