A 47-year-old woman was admitted to our Neurology Department with a 13-year history of slowly progressing atrophy and weakness of the upper extremities, and numerous masses in the supraclavicular regions. MRI examination (figure) revealed plexiform neurofibromas of the brachial plexuses, confirmed by biopsy. No other signs of neurofibromatosis (NF) were seen.This case represents mosaic localized NF1, which arises from somatic mutations occurring in a late-stage differentiated cell, with clinical manifestation restricted to a single region or organ.

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Aneurysms of the posterior cerebral artery (PCA) are uncommon (about 1% of all intracranial aneurysms) and their neurosurgical treatment is associated with high operative risk. We report on two saccular aneurysms of the P1 segment of the right PCA, combined with occlusion of the C1 segment of the internal carotid artery (ICA) detected during routine diagnostic studies in a 58-year-old patient with slight sensory loss in the left extremities. The aneurysms were embolized during two consecutive sessions, without subsequent complications. Endovascular intervention is an efficient method in the treatment of multiple aneurysms in the P1 segment of the PCA.