AbstractWe aim to define the prevalence of nephrolithiasis, the impact of anatomic and metabolic factors to stone formation and prognosis of patients with autosomal dominant polycystic kidney disease in Albania. We included 200 patients with autosomal dominant polycystic kidney from 2002 to 2009. The patients underwent X-ray, renal ultrasonography. We performed the metabolic evaluation of blood and urine. Survival times were calculated as the time to dialysis, transplantation, or death. Kaplan-Meier product-limit survival curves were constructed. Log rank test was used to compare the survival curves. Nephrolithiasis was present in 116 of our patients with autosomal dominant polycystic kidney disease (58%), with a mean age 46.4±5.7 years. Sixty five patients with kidney stones (56%) were women. The stones were composed primarily of urate (47%) and calcium oxalate (39%), and other compounds 14%. In 40% of patients the presence of stones was associated with a history of urinary tract infections and flank pain. In our study the prevalence of nephrolithiasis is 58%, higher than it reported in literature. Except anatomic and metabolic factors, there are other contributor factors to stone formation in our patients such socioeconomic status of patients, geographic zones and dietary habits.
lipoprotein colesterol (r ¼ -0.41, p ¼ 0.004). In males such significant correlations were not found.Conclusions: Cortisol can be considered as one of factors which regulate metabolic background of essential arterial hypertension. Its plasma concentration is dependent of gender and probably is associated with atherogenic dyslipidemia in hypertensive females.Objective: The metabolic syndrome (MetS) is recognized as a cluster of cardiovascular risk factors. We sought to study the prevalence of MetS, defined by the Adult Treatment Panel III criteria, in patients with Essential Hypertension.Methods: We studied 541 hypertensives (205 men), of median age 60 (range: 19-87) years. A health questionnaire was completed for all participants, including personal history of hypertension, diabetes mellitus (DM), ischemic heart disease (IHD), smoking habits and medications taken. The waist circumference and blood pressure were measured. Fasting blood samples were obtained in order to measure glucose, and a complete lipid profile.Results: Three hundred sixty one out of 541 patients (66.7%) met the criteria for MetS. MetS was more prevalent in females than in males (70.2% vs 61.0%, p < 0.05). The overall prevalence of MetS in hypertensives was about 3 fold higher compared with that of the general Greek population (20%).
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