Latar belakang: Penyakit Arteri Perifer (PAP) adalah penyumbatan pembuluh darah secara parsial hingga total pada pembuluh darah terutama di kaki. Nilai Ankle Brachial Index (ABI) merupakan alat untuk skrining dan diagnosis. Homosistein yang berlebihan di dalam tubuh merupakan faktor risiko dari PAP. Defisiensi asam folat, vitamin B6, dan vitamin B12 menganggu metabolisme homosistein dan meningkatkan risiko PAP secara tidak langsung. Metode: Penelitian ini merupakan penelitian potong lintang yang dilakukan di Rumah Sakit Islam Siti Hajar Kota Mataram. Jumlah sampel penelitian adalah 52 yang merupakan pasien penyakit arteri perifer dengan nilai ABI <0,90. Teknik pengambilan sampel menggunakan metode consecutive sampling. Analisis data menggunakan uji korelasi Spearman. Hasil: Rata-rata asupan asam folat, vitamin B6, dan vitamin B12 harian pada sampel penelitian kurang dari 50% angka kecukupan gizi harian yang dianjurkan untuk masyarakat Indonesia. Rata-rata nilai ABI yang diperoleh pada sampel penelitian adalah 0,79. Hasil uji korelasi Spearman antara nilai ABI dengan asupan asam folat menunjukkan signifikansi = 0,20 dan kekuatan korelasi 0,322. Hasil uji korelasi Spearman antara nilai ABI dengan asupan vitamin B6 menunjukkan signifikansi = 0,167. Hasil uji korelasi Spearman antara nilai ABI dengan asupan vitamin B12 menunjukkan signifikansi = 0,800. Simpulan: Terdapat hubungan yang signifikan antara nilai ABI dengan asupan asam folat dan hubungan yang tidak signifikan antara nilai ABI dengan vitamin B6 dan vitamin B12. Kata Kunci: Penyakit Arteri Perifer, Ankle Brachial Index, Asam Folat, Vitamin B6, Vitamin B12.
Aims The aim of this study was to determine the relationship between intake levels of folic acid, vitamin B6, and vitamin B12 with the value of the Ankle Brachial Index (ABI) in patients with peripheral artery disease in Mataram City. Methods and Results This study is a cross sectional study conducted at Siti Hajar Islamic Hospital in Mataram. The sample was patients with peripheral artery disease with an ABI value less than 0.90. The number of research samples was 52 subjects. Data Folic acid, vitamin B6, and vitamin B12 daily intake were collected using the 24-hours food recall method. The sampling technique used consecutive sampling method. Data analysis used the Spearman correlation test. The average daily intake of folic acid, vitamin B6, and vitamin B12 in the study sample wass less than 50% of the recommended daily nutritional adequacy rate for Indonesians. The average ABI in the sample was 0.79. The results of the Spearman correlation test between ABI and folic acid intake showed p value = 0.020 and r = 0.322. The results of the Spearman correlation test between the ABI and vitamin B6 intake showed p value = 0.167. The results of the Spearman correlation test between ABI and vitamin B12 intake showed p value = 0.800. Conclusion There is a significant relationship between ABI and folic acid intake. There is an insignificant relationship between ABI and vitamin B6 and vitamin B12.
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