Indonesia is known for its culture, one of which is traditional cosmetics that have been used by the ancestors of the Indonesian people for decades and have proven their efficacy. This heritage must be preserved because it is a national culture. Also, the effectiveness of this herb is not inferior to that of modern herbs. Traditional cosmetics are derived from plants, animals, minerals, galenic preparations, or a mixture of the four, which have been used for generations. This audit points to supply data around conventional beauty care products in Indonesia that are valuable for skin care, hair care, postnatal care, and vaginal care.
Tomatoes (Solanum lycopersicum Mill.), a common vegetable in Indonesia, contain high levels of lycopene, which is good for the body. This research further investigates the activity of polar and nonpolar fractions of tomatoes as elastase and tyrosinase inhibitory, and cytotoxic agents. The extraction procedure used is maceration, fractionation through liquid-liquid fractionation, purification of phytochemical substances is achieved through the application of thin layer chromatography. Elastase and tyrosinase inhibitory activity was analyzed using spectrophotometry and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide cytotoxic assay. The result showed that the extract yield was 0.004%. The percentage of polar fraction from the extract was 2.58%, while the nonpolar fraction was 0.69%. The elastase inhibitory activity of polar and nonpolar fractions of tomato extract is 87.21% ± 7.57% and 73.12% ± 7.44%, respectively, The elastase inhibitory activity of polar and nonpolar fractions of tomato extract is 87.21% ± 7.57% and 73.12% ± 7.44%, respectively. The fractions had higher the anti-elastase activity than the positive control quercetin (65.97% ± 3.00%). The tyrosinase inhibitory activity of polar and nonpolar fractions of tomato extract is 23.71% ± 7.91% and 41.16% ± 5.41% (kojic acid as standard is 65.07% ± 0.86%), respectively. The IC50 of the cytotoxic assay to NIH 3T3 mouse embryonic fibroblast cells of the polar and nonpolar fraction of tomato extract is 1820.90 μg/mL and 1643.86 μg/mL, respectively.
Keinginan untuk mempercantik diri dengan menggunakan kosmetik yang berlebihan menyebabkan masyarakat/ konsumen sering membuat kesalahan dalam memilih dan menggunakan kosmetik tanpa memperhatikan kondisi kulit dan kandungan bahan dasar kosmetik. Hal ini dapat menyebabkan berbagai masalah kelainan kulit karena kurangnya pengetahuan dalam pemilihan dan penggunaan kosmetik yang baik dan benar. Dalam hal ini maka diperlukannya penyuluhan untuk melindungi masyarakat dengan memberikan informasi yang benar, jelas dan jujur mengenai jaminan barang atau jasa kecantikan. Permasalahan mitra tersebut yang diangkat pada program pengabdian kepada masyarakat ini adalah pemberian penyuluan yan merupakan upaya preventif kepada masyarakat terkait bahan kimia berbahaya pada kosmetik dan legalitasnya. Hal ini dimaksudkan agar generaasi milenial dan ibu-ibu PKK Kelurahan Jatinegara Kaum - Kecamatan Pulo Gadung – Jakarta Timur – DKI Jakarta menjadi lebih bijak dalam memilih dan menggunakan kosmetik. Kegiatan pengabdian pada masyarakat ini dilaksanakan dengan menggunakan metode penyuluhan dengan presentasi, buku saku dan power point. Hasil dari program pengabdian kepada masyarakat ini adalah masyarakat Kelurahan Jatinegara Kaum - Kecamatan Pulo Gadung – Jakarta Timur – DKI Jakarta akan lebih berhati-hati dalam memilih dan menggunakan kosmetik yang baik dan aman, serta memperoleh pengetahuan tentang bahan kimia berbahaya dalam kosmetik yang selama ini mereka gunakan.
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