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Neutrophil extracellular traps (NETs) were described more than one decade ago, but recently, the interest in these structures has increased due to their involvement in cancer progression, cancer-related thrombosis, and development of metastasis. This protumoral role of NETs strengthens their potential as new prognostic markers of cancer.

Resumen: El sistema internacional de farmacovigilancia recopila información sobre eventos adversos por medicamentos a partir de informes emitidos por los médicos en la práctica clínica. Los reportes de reacciones adversas a medicamentos (RAM) son escasos. Diseñamos un cuestionario basado en una escala de Likert de cinco puntos. El cuestionario, de 24 preguntas, se administró a una muestra de médicos. Las respuestas de los cuestionarios indican que es importante contar con sistemas de farmacovigilancia. A pesar de ello, casi tres cuartos de los encuestados no sabían cómo informar de una reacción adversa y dos quintos no deseaban hacerlo. Tres cuartas partes de los encuestados expresaron que la instrucción sobre la elaboración de informes debería comenzar durante la carrera de Medicina. Los resultados sugieren que la elaboración de informes de RAM debe incluirse en la educación médica. Es necesario establecer protocolos que aseguren que los lineamientos para informar RAM sean fáciles de seguir. Es recomendable que los programas de capacitación y educación médica continua generen una conciencia de responsabilidad frente al reporte de RAM.Palabras clave: farmacovigilancia, sistemas de reporte de reacciones adversas a medicamentos, encuesta, cuestionario, responsabilidad Professional responsibility applied to drug surveillance: a study case in México Abstract: The international pharmacovigilance system collects adverse drug events reported by physicians in their clinical practice. Adverse drug reactions (ADR) reported are scarce. We designed a questionnaire based on a 5-point Likert scale. The questionnaire (24 questions) was administered to a sample of physicians in Mexico City. Questionnaire responses indicated that having pharmacovigilance systems is important. Despite this, nearly three quarters of respondents did not know how to report an adverse drug reaction, and two-fifths were not willing to do so. Three quarters believed that education regarding reporting and its methods should be initiated during medical school. The results from our questionnaire suggest that medical school training in ADR report writing should be implemented. Good protocols have to be in place to ensure that ADR report forms have easy-to-follow guidelines and are easy to complete. It is recommended that the programs of training and medical education generate conscience of responsability towards the report of ADRs.Key words: pharmacovigilance, adverse drug reaction reporting systems, survey, questionnaire, responsibilityResponsabilidade profissional aplicada à farmacovigilância: um estudo de caso no México Resumo: O sistema internacional de farmacovigilância recopila informação sobre eventos adversos por medicamentos a partir de informes emitidos pelos médicos na prática clínica. Os informes de reações adversas a medicamentos (RAM) são escassos. Idealizamos um questionário baseado numa escala de Likert de cinco pontos. O questionário, de 24 perguntas, foi administrado a uma mostra de médicos. As respostas dos questionários indicam que é im...

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