Se analizan las posibilidades de contribuir a la Educación patrimonial a través de la integración de la arqueología virtual (reconstrucciones y recreaciones virtuales, realidad aumentada, etc.) en propuestas didácticas planteadas desde diversas metodologías. Para ello se tienen en cuenta de diferentes proyectos de innovación y de investigación educativa que se han tenido como base visualización, manipulación, clasificación o construcción de objetos virtuales de carácter arqueológico, algunos de ellos en el entorno de la web social colaborativa o web 2.0. Palabras clave: didáctica del patrimonio, arqueología reconstructiva, realidad aumentada, web 2.0, ciencia ciudadana.

Background Because of the efficacy and good safety profile of antimalarials in systemic lupus erythematosus (SLE), hydroxychloroquine (HCQ) is currently recommended in all SLE patients. However, patients’ compliance was reported as suboptimal. This study aims to elucidate the reasons for discontinuing antimalarials in a large series of SLE patients followed in a single centre during the last 50 years. Material and methods Among all patients diagnosed between 1968 and 2017 at our reference centre, retrospective data were obtained from electronic medical records of SLE patients consecutively visited during 2015–2017 and controlled for at least 1 year. Demographic, clinical, laboratory and therapeutic data at disease onset and during the follow-up in the whole cohort and differences between SLE patients discontinuing and continuing on antimalarials were analysed. Results Five-hundred thirty-nine patients followed during a median of 19 years were analysed. Median age at disease diagnosis was 29 years and 91.8% were women. Antimalarials were initiated by 521 (96.7%) patients and 18 (3.3%) cases did not start them mainly because of a quiescent or life-threatening SLE disease. In the 129 (24.7%) patients starting antimalarials with subsequent discontinuation, median treatment duration was 8.4 years. The main reason leading to treatment cessation was drug toxicity in 97 (18.6%) patients, of which macular toxicity was the most frequent adverse effect (n = 80; 15.3%). Treatment was stopped because of patient’s preference in 13 (2.5%) cases. The factors independently associated with antimalarial discontinuation were age at the end of follow-up (OR 1.130, 95% CI 1.005–1.269, p = 0.040), duration on antimalarials (OR 0.872, 95% CI 0.841–0.903, p < 0.001), presence of hepatitis C virus infection (HCV) (OR 13.948, 95% CI 1.321–147.324, p = 0.028) and anti-β2-glycoprotein 1 antibodies (OR 2.275, 95% CI 1.146–4.517, p = 0.019). Conclusions In our 50 years-experience, almost all SLE patients underwent antimalarials. These drugs are usually stopped because of adverse effects, particularly macular toxicity. After a long-term follow-up, patients’ compliance to antimalarials was considerably high in our SLE patients.

El combat de Raïmats, succeït el darrer dia de la batalla de l’Ebre (15 de novembre de 1938) ha estat investigat des de diverses òptiques per part del grup de recerca DIDPATRI en una perspectiva interdisciplinar i transversal. La recerca va començar amb una petició de l’associació cívica Lo Riu el 2013 a la Universitat de Barcelona que van aconduir a una intensa campanya arqueològica en una clara dinàmica de recerca pública. En els anys posteriors i fins el 2018 les accions sobre Raïmats s’han multiplicat incorporant experiències sobre museografia a l’aire lliure;  visites escolars; turisme de camps de batalla; recreació històrica i generació d’iconografia didàctica. Tot plegat la dinàmica no exhaurida, es contextualitza també en una dinàmica pedagògica d’investigació acció en la qual els plantejaments didàctics assoleixen protagonisme. L’experiència transversal de Raïmats incorpora també una vessant explícita de memòria en tant que el lloc s’ha convertit en un referent significatiu de la batalla de l’Ebre.