This article describes the work of a mental health team confronting the individual and social consequences of human rights violations by the military government in Chile from 1973 through 1989. It examines three forms of repression—torture, disappearance, and death—and the consequences these have had for victims and family members. Damage to victims is conceptualized in terms of “extreme traumatization,” and psychotherapeutic work with the victims has required radical rethinking of the nature of the therapeutic bond that is necessary with these patients. Grief processes have special relevance in this work, as does the relationship between the personal experience of repression and the sociopolitical context. An illustrative case study of therapy with a torture victim is presented. Finally, the article emphasizes the importance of societal reparation for the psychological recovery of the victims and the consolidation of a stable democracy in Chile.

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Multiple non-related neoplasia does not have an established approach or benefits for performing whole-exome sequencing (WES) analysis. We report on a 46-year-old woman who developed astrocytoma, thyroid, and breast cancer within 10 years. The WES analysis found a novel missense variant in the ACSL6 gene, and the protein modeling showed altered secondary and tertiary structures, which modify the binding to cofactors and substrates. ACSL6 is involved in lipid metabolism, expressed in the brain, thyroid, and breast tissues, and is associated with diverse types of cancer. Our study demonstrates the benefit of WES analysis compared with commercial panels in patients with non-related neoplasia.

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Ferroviarias). Sus investigaciones están relacionadas con temas diversos: medios de transporte (servicios e infraestructuras) (terrestre, aéreo y marítimo-portuario), sectores regulados, administración electrónica, protección ambiental, servicios públicos, derechos fundamentales, seguridad pública, e innovación docente en estudios jurídicos. Evaluadora externa y colaboradora permanente en varias revistas jurídicas. Miembro del Grupo de Investigación Administraciones Públicas, libertades públicas y políticas sectoriales (SEJ-582).