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Abstract:We performed a systematic review to map the evidence and analyze the effect of whey protein supplementation in the elderly submitted to resistance training. Methods: A comprehensive search on Medline, LILACS, EMBASE and the Cochrane Library for relevant publications was conducted until August 2015. The terms used in the search were: "Resistance Training"; "Whey protein"; "elderly". Two authors independently assessed abstracts, texts in full and made critical appraisal. Results: A total of 632 studies were screened. Five studies were included composing a sample of 391 patients. The supplement whey protein was associated with higher total protein ingestion 9.40 (95% CI 4.03 to 14.78), and with an average change in plasma leucine concentration ranging from 406µmol/L to 490µmol/L compared with the control group. The supplementation was also associated with increased mixed muscle protein synthesis 1.26 (95% CI 0.46 to 2.07) compared to control group. Just one trial compared lean body mass in the group receiving whey protein supplementation and the control group (n=80) 0.07 (95% CI -0.37 to 0.51). Conclusion: We observed an increase in total protein intake, resulting in increased concentration of leucine and mixed muscle protein synthesis rate. No significant increase related to muscle mass or strength were observed.

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Background: Non-puerperal uterine inversions are rare. The objective of the study was to investigate the frequency, causes, clinical presentations, and management of published case reports of non-puerperal uterine inversion. Material and Methods: We searched MEDLINE, EMBASE, LILACS, the Cochrane Central Register of Controlled Trials, IBECS, BIOSIS, the Web of Science, SCOPUS, Conference Abstracts, and grey literature (Google scholar; the British Library) for papers published from January 1940 through March 2017. Results: We found a total of 170 case reports. The most common cause was leyomioma (57.2%) followed by sarcoma (13.5%). The definitive treatment of most cases was hysterectomy (86.8%). The median hemoglobin levels were seven, showing the severity of the condition by previous vaginal bleeding. All reported cases had a correct management demonstrated by the prognosis until hospital discharge. All patients were discharged, most of them without serious postoperative events. Cancer cases were referred for proper treatment. Only 2 cases of death were reported in 6 weeks and 3 months, respectively, both cases of cancer in advanced stages. Conclusion: Non-puerperal uterine inversion is rare. There have been 170 cases reports in the literature since 1940.