Introduction: Sleep is defined as the natural, periodic and reversible decrease in perception of the external environment, with the preservation of a certain degree of reactivity to the environment and autonomous functions. Sleep consists of 2 phases, REM phase and NREM phase, these phases alternate at night in the form of five to six cycles; of which the NREM phase is 75% presented and the REM by 25%.Thertita mark: Caffeine is a readily available short-acting stimulant that has been shown to reduce some of the deficits associated with sleep loss. With the rubber mark the absorption is carried out on the oral mucosa, which generates a greater bioavailability of the active substance and an immediate mechanism of action. The effective response dose can range from 100 mg to 200 mg and the effect arises from 6 min of administered the active substance. It is important to note that the dose of caffeine in chewing gum is directly proportional to the effects on sleep inertia, as well as the duration and maintenance of them.Discussion: Being able to analyze the mechanisms of action of caffeine on sleep inertia, helps us to make a comparison of chewing gum with caffeine vs placebo (simple gum). Chewing generates for a short period of time the maintenance of performance on simple and complex tasks and improves alertness, with caffeine these same effects look prolonged for longer. Conclusion:Caffeinated gum is an effective therapeutic presentation on sleep inertia. The dosage for a positive response ranges from 75 to 200 mg depending on the circumstances of sleep restriction. That is, thanks to the effects generated by chewing on the state of alertness and cognition and the potentialization and duration of them by caffeine.

Sleep disorders cause alterations in the quality of life of each and every patient. At least two thirds of those suffering from chronic degenerative diseases are affected by sleep disorders, the most frequent being the female sex. Many individuals are subjected to night work where a constant alertness is required and it has been scientifically proven how this affects the quality of life of each employee; Well, sleep is one of the most essential pillars of daily life, since it maintains critical aspects of cognition for optimal mental performance, as well as in mood, alertness and performance during the work and activities of everyday life. Waking up abruptly implies something known as "sleep inertia," which is characterized by impaired performance and subjective lack of alert for a transitional period, which hardly progresses to good cognition. It is well known that chewing facilitates concentration, maintains alertness and