We study the possibility that large-scale magnetic fields observed in galaxies could be produced by a dark matter halo made of charged ultra-light bosons, that arise as excitations of a complex scalar field described by the Klein-Gordon equation with local U (1) symmetry which introduces electromagnetic fields that minimally couple to the complex scalar current and act as dark virtual photons. These virtual photons have an unknown coupling constant with real virtual photons. We constrain the final interaction using the observed magnetic fields in galaxies. We use classical solutions of the Klein-Gordon-Maxwell system to describe the density profile of dark matter and magnetic fields in galaxies. We consider two cases assuming spherical and dipolar spatial symmetries. For the LSB spherical galaxy F563-V2, we test the sensitivity of the predicted rotation curves in the charged Scalar Field Dark Matter (cSFDM) model to variations of the electromagnetic coupling and using the Fisher matrix error estimator, we set a constraint over that coupling by requiring that theoretical rotation curves lay inside the 1σ confidence region of observational data. We find that cSFDM haloes generate magnetic fields of the order of μG and reproduce the observed rotation curves of F563-V2 if the ultra-light boson has a charge ∼< 10 −13 e for the monopole-like density profile and ∼< 10 −14 e for the dipolelike one.
IIBackground: Cannabinoids and their principle psychoactive target, the cannabinoid type 1 receptor (CB1R), impact a number of alcohol-related properties, and although alcohol and cannabis are often co-used, particularly in adolescence, few animal models of this phenomenon exist. We modeled the couse of alcohol and Δ 9 -tetrahydrocannabinol (THC) in adolescent mice using ingestive methods popular during this developmental period in humans, namely binge-drinking and edible THC. With this model, we assessed levels of use, acute effects, and tolerance to each substance.Methods: Adolescent male C57BL/6J mice had daily, limited access to 1 of 2 edible doughs (THC or control), to 1 of 2 fluids (ethanol (EtOH) or water), and in 1 of 2 orders (dough-fluid or fluiddough). Home cage locomotor activity was recorded both during access and after access. On the day following the final access session, a subset of mice were assessed for functional and metabolic tolerance to alcohol using accelerating rotarod and blood EtOH concentrations, respectively. The remaining mice were assessed for tolerance to THC-induced hypothermia, and whole-brain CB1R expression was assessed in all mice.Results: EtOH intake was on par with levels previously reported in adolescent mice. Edible THC was well-consumed, but consumption decreased at the highest dose provided. Locomotor activity increased following EtOH intake and decreased following edible THC consumption, and edible THC increased fluid intake in general. The use of alcohol produced neither functional nor metabolic tolerance to an alcohol challenge. However, the use of edible THC impaired subsequent drug-free rotarod performance and was associated with a reduction in THC's hypothermic effect.Conclusions: Adolescent mice self-administered both alcohol and edible THC to a degree sufficient to acutely impact locomotor activity. However, only edible THC consumption had lasting effects during short-term abstinence. Thus, this adolescent co-use model could be used to explore sex differences in self-administration and the impact substance co-use might have on other domains such as mood and cognition.
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