This meta-analysis of 172 studies (N = 2,263 anxious,N = 1,768 nonanxious) examined the boundary conditions of threat-related attentional biases in anxiety. Overall, the results show that the bias is reliably demonstrated with different experimental paradigms and under a variety of experimental conditions, but that it is only an effect size of d = 0.45. Although processes requiring conscious perception of threat contribute to the bias, a significant bias is also observed with stimuli outside awareness. The bias is of comparable magnitude across different types of anxious populations (individuals with different clinical disorders, high-anxious nonclinical individuals, anxious children and adults) and is not observed in nonanxious individuals. Empirical and clinical implications as well as future directions for research are discussed.

Two extant evolutionary models, biological sensitivity to context theory (BSCT) and differential susceptibility theory (DST), converge on the hypothesis that some individuals are more susceptible than others to both negative (risk-promoting) and positive (development-enhancing) environmental conditions. These models contrast with the currently dominant perspective on personal vulnerability and environmental risk: diathesis stress/dual risk. We review challenges to this perspective based on emerging theory and data from the evolutionary, developmental, and health sciences. These challenges signify the need for a paradigm shift in conceptualizing Person x Environment interactions in development. In this context we advance an evolutionary--neurodevelopmental theory, based on DST and BSCT, of the role of neurobiological susceptibility to the environment in regulating environmental effects on adaptation, development, and health. We then outline current thinking about neurogenomic and endophenotypic mechanisms that may underpin neurobiological susceptibility, summarize extant empirical research on differential susceptibility, and evaluate the evolutionary bases and implications of BSCT and DST. Finally, we discuss applied issues including methodological and statistical considerations in conducting differential susceptibility research; issues of ecological, cultural, and racial--ethnic variation in neurobiological susceptibility; and implications of differential susceptibility for designing social programs. We conclude that the differential susceptibility paradigm has far-reaching implications for understanding whether and how much child and adult development responds, for better and for worse, to the gamut of species-typical environmental conditions.

Is early preventive intervention effective in enhancing parental sensitivity and infant attachment security, and if so, what type of intervention is most successful? Seventy studies were traced, producing 88 intervention effects on sensitivity (n = 7,636) and/or attachment (n = 1,503). Randomized interventions appeared rather effective in changing insensitive parenting (d = 0.33) and infant attachment insecurity (d = 0.20). The most effective interventions used a moderate number of sessions and a clear-cut behavioral focus in families with, as well as without, multiple problems. Interventions that were more effective in enhancing parental sensitivity were also more effective in enhancing attachment security, which supports the notion of a causal role of sensitivity in shaping attachment.

About a decade ago, the Adult Attachment Interview (AAI; C. George, N. Kaplan, & M. Main, 1985) was developed to explore parents' mental representations of attachment as manifested in language during discourse of childhood experiences. The AAI was intended to predict the quality of the infant-parent attachment relationship, as observed in the Ainsworth Strange Situation, and to predict parents' responsiveness to their infants' attachment signals. The current meta-analysis examined the available evidence with respect to these predictive validity issues. In regard to the 1st issue, the 18 available samples (N = 854) showed a combined effect size of 1.06 in the expected direction for the secure vs. insecure split. For a portion of the studies, the percentage of correspondence between parents' mental representation of attachment and infants' attachment security could be computed (the resulting percentage was 75%; kappa = .49, n = 661). Concerning the 2nd issue, the 10 samples (N = 389) that were retrieved showed a combined effect size of .72 in the expected direction. According to conventional criteria, the effect sizes are large. It was concluded that although the predictive validity of the AAI is a replicated fact, there is only partial knowledge of how attachment representations are transmitted (the transmission gap).

Dunng the past 10 years nearly 80 studies on disoigamzed attachment mvolvmg moie than 6 000 mfanl-paient dyads have been cained out The cunent series ot meta-analyscs have estabhshed the lehabihty and disuimmant vahdity of disoigamzed mfant attachment Although disorganized attachment behavioi is necessanly difficult to observe and often subtle, many reseaichers have managed to become rehable codeis Fuitheimoie, disoigamzed attachment shows modest shoit-and long term stabihty, in paiticular in middle class envnonments and it is not just a concomitant of constitutional, temperamental, or physical child pioblems The prediclive vahdity of disorganized attachment is estabhshed in terms of pioblematic strcss management, the elevated nsk of externahzmg problem behavior, and even the tendency of disorganized infants to show dissociative behavioi later in life In noimal middle class families about 15% of the infants develop disorganized attachment behavioi In other social contexts and in chnical groups this percentage may become twice 01 even thiee times highei (e g in the case of maltreatment) Although the importance of disorganized attachment foi developmental psychopathology is evident the seatch foi the mechanisms leading to disoiganization has just started Fiightemng parental behavioi may play an important role but it does not seem to be the only causal factoi mvolved in the emergence of disoigamzed attachment