Summary:fusion of PBSC and the i. -106). The incidence of infectiousWe present our experience at the Instituto Nacional de Cancerología in Mexico, with the installation and care of complications was 2.2 ؋ 1000 catheter-days (1.7 Permacath and 3.0 Mahurkar); during neutropenia it was an IVTT including apheresis collection, reinfusion of PBSC and intravenous and hematological support of patients 3.7 ؋ 1000 cathether-days. The incidence of thrombosis was 0.9 ؋ 1000 catheter-days. There was a total of seven undergoing PBSCT in whom a high-flow catheter (Mahurkar or Permacath) was installed between November infectious episodes (12.7%). Five (9%) were local and two were (3.6%) bacteremias. The microorganism most 1992 and June 1994. commonly isolated was Staphylococcus sp. (57%). Four catheters (7.1%) were removed because of complications: one thrombosis and three infections. Both cathMaterials and methods eters have proven useful and safe for long-lasting vascular access in patients undergoing PBSCT. No statistical Catheter difference was found in infectious and non-infectiousThe devices utilized were either a Mahurkar (Quinton complications between either catheters.Instrument, Seattle, WA, USA) double lumen nontunneled Keywords: peripheral blood stem cell transplantation; siliconized catheter or a Permacath (Quinton Instrument) apheresis catheters; intravenous therapy team silastic, double lumen, Dacron felt cuff tunneled catheter. Both catheters are imported to Mexico, and the choice of which one to place in a patient was based solely on availPeripheral blood stem cell transplantation (PBSCT) is a ability. new therapeutic approach for supporting treatment with high-dose chemotherapy.

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Colorectal carcinoma is a tumour that very infrequently gives rise to cutaneous metastases and when it does so, it is rarely via the haematogenous route. We present the case of a 55-year old male diagnosed with an adenocarcinoma of the rectum (lower third), clinical stage T3N2M0. Initially treated with neoadjuvant radiochemotherapy, he was operated on eight weeks later, with an extended abdominoperineal amputation. The anatomopathological result was mucinous adenocarcinoma of the rectum, clinical stage ypT3bN1. Following a postoperative period without complications, the patient received chemotherapeutic treatment with capecitabine. Eighteen months later the patient reported the progressive appearance of subcutaneous nodules in different localizations. In the computerized tomography test multiple images were objectivized suggesting metastasis at the hepatic and pulmonary levels, as well as subcutaneous lesions. The biopsy-excision of one of the subcutaneous nodules corroborated the suspicion of metastasis of the adenocarcinoma of the rectum. Chemotherapy treatment was considered for the patient, which was not administered due to the rapid deterioration of the patient leading to his death.