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Introduction: Existing nomograms predicting lymph node involvement (LNI) in prostate cancer (PCa) are based on conventional lymphadenectomy. The aim of the study was to develop the first nomogram for predicting LNI in PCa patients undergoing sentinel guided pelvic lymph node dissection (sPLND). Materials and Methods: Analysis was performed on 1,296 patients with PCa who underwent radioisotope guided sPLND and retropubic radical prostatectomy (2005-2010). Median prostate specific antigen (PSA): 7.4 ng/ml (IQR 5.3-11.5 ng/ml). Clinical T-categories: T1: 54.8%, T2: 42.4%, T3: 2.8%. Biopsy Gleason sums: ≤6: 55.1%, 7: 39.5%, ≥8: 5.4%. Multivariate logistic regression models tested the association between all of the above predictors and LNI. Regression-based coefficients were used to develop a nomogram for predicting LNI. Accuracy was quantified using the area under the curve (AUC). Results: The median number of LNs removed was 10 (IQR 7-13). Overall, 17.8% of patients (n = 231) had LNI. The nomogram had a high predictive accuracy (AUC of 82%). All the variables were statistically significant multivariate predictors of LNI (p = 0.001). Univariate predictive accuracy for PSA, Gleason sum and clinical stage was 69, 75 and 69%, respectively. Conclusions: The sentinel nomogram can predict LNI at a sPLND very accurately and, for the first time, aid clinicians and patients in making important decisions on the indication of a sPLND. The high rate of LN+ patients underscores the sensitivity of sPLND.

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This paper historicizes the idea of “popular science” in the Ukrainian academic discourse in relation to contemporary approaches to “national science” (as “science proper”) and places special emphasis on the introduction of regular scientific lectures to public audiences in early twentieth century Habsburg Galicia. The Shevchenko Scientific Society was the central Ukrainian association of scholars and scientists at the time. Male-dominated, and increasingly dedicated to “Ukrainoznavstvo” (“Ukrainian studies”), the Shevchenko Scientific Society paid little attention to the popularization of scientific research. The Petro Mohyla Society for Ukrainian Scientific Lectures emerged in reaction to the Shevchenko Society. Its goal was to expand public awareness of the scientific work, and its members proceeded to organize regular public lectures all over Galicia between 1909 and 1914. This paper analyzes such popularization of science, propagated by the Petro Mohyla Society, and examines the lecture audiences with regard to their location, gender, and respective interests.