Background: Sedative hypnotic/antipsychotic poisoning represented 5.84% of cases according to national poison data system in 2017. In Egypt, studies about antipsychotic poisoning are scarce. Objectives: is to assess the pattern of toxicity and prognosis of cases with acute antipsychotic poisoning admitted to Tanta University Poison Control Unit. Patients and Methods: This study was conducted on cases who admitted to Tanta University Poison Control Unit with acute antipsychotics poisoning. All cases were subjected to clinical evaluation, laboratory investigations and electrocardiogram. Severity was assessed by poison severity score. Results: Majority of cases were represented equally in age groups (0-10) and (11-20) years with 33.3% for each age group, 65% of cases were females, most of cases were from urban areas (71.7%) and singles (71.7%). History of mental disorder found in 31.6% of cases and suicidal attempts represented the most common manner of poisoning (71.7%). Clozapine was the highest antipsychotic drug taken (35%) and 6.7% of cases developed extrapyramidal manifestations. Miosis was found in 56.7% of cases. Tachycardia was recorded in 46.7% of cases and QTc interval was prolonged in 43% of cases. According to poison severity score, most studied cases were either mild (51.7%) or moderate (33.7%). One case was admitted to ICU. Multiple regression analysis showed that decreased GCS, PCO2, O2 saturation were associated with increased hospital stay. Conclusion: Antipsychotic poisoning was commonly mild to moderate. Neurological and cardiovascular manifestations were the predominant. Sinus tachycardia and prolonged QTc were the most common electrocardiographic changes. Antipsychotic poisoning usually had a good prognosis.

Aim: The primary aim of this cross-sectional research study was to investigate the potential differences in perceived psychological stress level in those dieting compared to those not undertaking a diet. The secondary objective was to assess if stress levels in those dieting were correlated with the duration of the diet. Methods:We administered the previously validated Perceived Stress Scale (PSS) to 60 United Arab Emirates residents. Participants were also asked demographic questions concerning age and gender and were requested to indicate if they were currently undertaking a diet to achieve weight loss. Participants who were actively on a diet were also asked about the duration of the diet (days). Results: A total of 60 participants were recruited to the study, of which 71.7% were female. The majority (71.7%) of the sample were 18-25 years old and 58.3% indicated that they were undertaking a diet at the time of data acquisition. The median total score on the PSS was 19 (14 -22). There was a significant difference in PSS total score between those on a diet and those not (p = 0.021). A positive correlation was found between number of days on a diet and perceived stress level (r = 0.147) but this was not statistically significant (p = 0.406). Conclusions: Dieting behaviour was associated with higher levels of perceived psychological stress compared to those not undertaking a diet.Engaging in dieting behaviour is commonly driven by body dissatisfaction and may be linked to heightened stress due to social pressures or other factors.

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