Vessel constriction followed by dilatation is a postulated mechanism for migraine, although there is no definitive evidence for this.2 Aside from these two conditions, reversible constriction of arteries is not a recognized cause of cerebrovascular disease.We describe the clinical and angiographic syndrome of four patients with reversible constriction of the cerebral vasculature. We also review some of the relevant literature and discuss the nosology of this only recently recognized condition. Case Reports Case IA 48-year-old woman was admitted to the hospital because of a severe headache that was associated with a sense of spinning, nausea, vomiting, and blurred vision. Headaches were unusual for her, and there was no personal or family history of migraine.Initially, her blood pressure was 200/100 mm Hg, but it quickly fell to the 120/65 mm Hg range without

Cocaine abuse may contribute to the diverse forms of renal injury. We report a case of a pregnant woman who developed a large subcapsular renal haematoma after cocaine intoxication at 18-week gestation. She stabilized on conservative management and presented again at 29-week gestation with pre-eclampsia, acute renal failure and fetal demise. She required caesarean section delivery and intensive antihypertensive therapy to control severe pre-eclampsia associated with cocaine intoxication. This case is unique in that it is the first report of cocaine intoxication in pregnancy complicated by subcapsular haemorrhage. We discuss the possible mechanisms for the occurrence of this complication.

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