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Some psychological and physiological reactions to introduction of chlordiaze‐poxide hydrochloride to an experimental situation involving a conformity trial were investigated. Groups of four subjects were selected with either considerable previous acquaintance (Friends) or little acquaintance (Strangers). In each group, two subjects were given an injection of the drug and two an injection of saline. Conformity to false group feedback was measured on a Crutchfield‐Gerard apparatus and arousal was measured in terms of the plasma free fatty acid (FFA) level. Self‐ratings of mood were obtained using the Nowlis Adjective Check List. It was found that the experimental manipulations of group composition or drug injection did not yield clear‐cut results unless the subjects were divided according to initial ratings of anxiety. Subjects initially more anxious, who were administered the drug and who were tested as Strangers, showed greater conformity to group pressure and a continuous increase in physiological arousal. These conditions were interpreted as being cumulative sources of strain, under which subjects concentrate on monitoring themselves to the exclusion of attending to surrounding events.