We propose an adaptive robust control for a second order nonlinear model of the interaction between cancer and immune cells of the body to control the growth of cancer and maintain the number of immune cells in an appropriate level. Most of the control approaches are based on minimizing the drug dosage based on an optimal control structure. However, in many cases, measuring the exact quantity of the model parameters is not possible. This is due to limitation in measuring devices, variational and undetermined characteristics of micro-environmental factors. It is of great importance to present a control strategy that can deal with these unknown factors in a nonlinear model.
This paper presents a control strategy based on a new notion of time-varying fixed-time convergent control barrier functions (TFCBFs) for a class of coupled multiagent systems under signal temporal logic (STL) tasks. In this framework, each agent is assigned a local STL task regradless of the tasks of other agents. Each task may be dependent on the behavior of other agents which may cause conflicts on the satisfaction of all tasks. Our approach finds a robust solution to guarantee the fixed-time satisfaction of STL tasks in a least violating way and independent of the agents' initial condition in the presence of undesired violation effects of the neighbor agents. Particularly, the robust performance of the task satisfactions can be adjusted in a user-specified way.
We construct compositional continuous approximations for an interconnection of infinitely many discrete-time switched systems. An approximation (known as abstraction) is itself a continuous-space system, which can be used as a replacement of the original (known as concrete) system in a controller design process. Having synthesized a controller for the abstract system, the controller is refined to a more detailed controller for the concrete system. To quantify the mismatch between the output trajectory of the approximation and of that the original system, we use the notion of socalled simulation functions. In particular, each subsystem in the concrete network and its corresponding one in the abstract network is related through a local simulation function. We show that if the local simulation functions satisfy a certain smallgain type condition developed for a network of infinitely many subsystems, then the aggregation of the individual simulation functions provides an overall simulation function between the overall abstraction and the concrete network. For a network of linear switched systems, we systematically construct local abstractions and local simulation functions, where the required conditions are expressed in terms of linear matrix inequalities and can be efficiently computed. We illustrate the effectiveness of our approach through an application to frequency control in a power gird with a switched (i.e. time-varying) topology.
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